Daily Papers

Lung diseases represent a significant global health challenge, with Chest X-Ray (CXR) being a key diagnostic tool due to their accessibility and affordability. Nonetheless, the detection of pulmonary lesions is often hindered by overlapping bone structures in CXR images, leading to potential misdiagnoses. To address this issue, we developed an end-to-end framework called BS-LDM, designed to effectively suppress bone in high-resolution CXR images. This framework is based on conditional latent diffusion models and incorporates a multi-level hybrid loss-constrained vector-quantized generative adversarial network which is crafted for perceptual compression, ensuring the preservation of details. To further enhance the framework's performance, we introduce offset noise and a temporal adaptive thresholding strategy. These additions help minimize discrepancies in generating low-frequency information, thereby improving the clarity of the generated soft tissue images. Additionally, we have compiled a high-quality bone suppression dataset named SZCH-X-Rays. This dataset includes 818 pairs of high-resolution CXR and dual-energy subtraction soft tissue images collected from a partner hospital. Moreover, we processed 241 data pairs from the JSRT dataset into negative images, which are more commonly used in clinical practice. Our comprehensive experimental and clinical evaluations reveal that BS-LDM excels in bone suppression, underscoring its significant clinical value.

Chest X-rays (CXRs) are commonly utilized as a low-dose modality for lung screening. Nonetheless, the efficacy of CXRs is somewhat impeded, given that approximately 75% of the lung area overlaps with bone, which in turn hampers the detection and diagnosis of diseases. As a remedial measure, bone suppression techniques have been introduced. The current dual-energy subtraction imaging technique in the clinic requires costly equipment and subjects being exposed to high radiation. To circumvent these issues, deep learning-based image generation algorithms have been proposed. However, existing methods fall short in terms of producing high-quality images and capturing texture details, particularly with pulmonary vessels. To address these issues, this paper proposes a new bone suppression framework, termed BS-Diff, that comprises a conditional diffusion model equipped with a U-Net architecture and a simple enhancement module to incorporate an autoencoder. Our proposed network cannot only generate soft tissue images with a high bone suppression rate but also possesses the capability to capture fine image details. Additionally, we compiled the largest dataset since 2010, including data from 120 patients with high-definition, high-resolution paired CXRs and soft tissue images collected by our affiliated hospital. Extensive experiments, comparative analyses, ablation studies, and clinical evaluations indicate that the proposed BS-Diff outperforms several bone-suppression models across multiple metrics. Our code can be accessed at https://github.com/Benny0323/BS-Diff.

Chest X-Ray (CXR) imaging for pulmonary diagnosis raises significant challenges, primarily because bone structures can obscure critical details necessary for accurate diagnosis. Recent advances in deep learning, particularly with diffusion models, offer significant promise for effectively minimizing the visibility of bone structures in CXR images, thereby improving clarity and diagnostic accuracy. Nevertheless, existing diffusion-based methods for bone suppression in CXR imaging struggle to balance the complete suppression of bones with preserving local texture details. Additionally, their high computational demand and extended processing time hinder their practical use in clinical settings. To address these limitations, we introduce a Global-Local Latent Consistency Model (GL-LCM) architecture. This model combines lung segmentation, dual-path sampling, and global-local fusion, enabling fast high-resolution bone suppression in CXR images. To tackle potential boundary artifacts and detail blurring in local-path sampling, we further propose Local-Enhanced Guidance, which addresses these issues without additional training. Comprehensive experiments on a self-collected dataset SZCH-X-Rays, and the public dataset JSRT, reveal that our GL-LCM delivers superior bone suppression and remarkable computational efficiency, significantly outperforming several competitive methods. Our code is available at https://github.com/diaoquesang/GL-LCM.

Chest X-ray imaging (CXR) is an important diagnostic tool used in hospitals to assess patient conditions and monitor changes over time. Generative models, specifically diffusion-based models, have shown promise in generating realistic synthetic X-rays. However, these models mainly focus on conditional generation using single-time-point data, i.e., typically CXRs taken at a specific time with their corresponding reports, limiting their clinical utility, particularly for capturing temporal changes. To address this limitation, we propose a novel framework, EHRXDiff, which predicts future CXR images by integrating previous CXRs with subsequent medical events, e.g., prescriptions, lab measures, etc. Our framework dynamically tracks and predicts disease progression based on a latent diffusion model, conditioned on the previous CXR image and a history of medical events. We comprehensively evaluate the performance of our framework across three key aspects, including clinical consistency, demographic consistency, and visual realism. We demonstrate that our framework generates high-quality, realistic future images that capture potential temporal changes, suggesting its potential for further development as a clinical simulation tool. This could offer valuable insights for patient monitoring and treatment planning in the medical field.

Chest X-Ray (CXR) report generation is a promising approach to improving the efficiency of CXR interpretation. However, a significant increase in diagnostic accuracy is required before that can be realised. Motivated by this, we propose a framework that is more inline with a radiologist's workflow by considering longitudinal data. Here, the decoder is additionally conditioned on the report from the subject's previous imaging study via a prompt. We also propose a new reward for reinforcement learning based on CXR-BERT, which computes the similarity between reports. We conduct experiments on the MIMIC-CXR dataset. The results indicate that longitudinal data improves CXR report generation. CXR-BERT is also shown to be a promising alternative to the current state-of-the-art reward based on RadGraph. This investigation indicates that longitudinal CXR report generation can offer a substantial increase in diagnostic accuracy. Our Hugging Face model is available at: https://huggingface.co/aehrc/cxrmate and code is available at: https://github.com/aehrc/cxrmate.

Chest X-rays (CXRs) are the most frequently performed imaging test in clinical practice. Recent advances in the development of vision-language foundation models (FMs) give rise to the possibility of performing automated CXR interpretation, which can assist physicians with clinical decision-making and improve patient outcomes. However, developing FMs that can accurately interpret CXRs is challenging due to the (1) limited availability of large-scale vision-language datasets in the medical image domain, (2) lack of vision and language encoders that can capture the complexities of medical data, and (3) absence of evaluation frameworks for benchmarking the abilities of FMs on CXR interpretation. In this work, we address these challenges by first introducing CheXinstruct - a large-scale instruction-tuning dataset curated from 28 publicly-available datasets. We then present CheXagent - an instruction-tuned FM capable of analyzing and summarizing CXRs. To build CheXagent, we design a clinical large language model (LLM) for parsing radiology reports, a vision encoder for representing CXR images, and a network to bridge the vision and language modalities. Finally, we introduce CheXbench - a novel benchmark designed to systematically evaluate FMs across 8 clinically-relevant CXR interpretation tasks. Extensive quantitative evaluations and qualitative reviews with five expert radiologists demonstrate that CheXagent outperforms previously-developed general- and medical-domain FMs on CheXbench tasks. Furthermore, in an effort to improve model transparency, we perform a fairness evaluation across factors of sex, race and age to highlight potential performance disparities. Our project is at https://stanford-aimi.github.io/chexagent.html.

Purpose: Recent advancements in large language models (LLMs) have expanded their capabilities in a multimodal fashion, potentially replicating the image interpretation of human radiologists. This study aimed to develop open-source multimodal large language model for interpreting chest X-ray images (CXR-LLaVA). We also examined the effect of prompt engineering and model parameters such as temperature and nucleus sampling. Materials and Methods: For training, we collected 659,287 publicly available CXRs: 417,336 CXRs had labels for certain radiographic abnormalities (dataset 1); 241,951 CXRs provided free-text radiology reports (dataset 2). After pre-training the Resnet50 as an image encoder, the contrastive language-image pre-training was used to align CXRs and corresponding radiographic abnormalities. Then, the Large Language Model Meta AI-2 was fine-tuned using dataset 2, which were refined using GPT-4, with generating various question answering scenarios. The code can be found at https://github.com/ECOFRI/CXR_LLaVA. Results: In the test set, we observed that the model's performance fluctuated based on its parameters. On average, it achieved F1 score of 0.34 for five pathologic findings (atelectasis, cardiomegaly, consolidation, edema, and pleural effusion), which was improved to 0.46 through prompt engineering. In the independent set, the model achieved an average F1 score of 0.30 for the same pathologic findings. Notably, for the pediatric chest radiograph dataset, which was unseen during training, the model differentiated abnormal radiographs with an F1 score ranging from 0.84 to 0.85. Conclusion: CXR-LLaVA demonstrates promising potential in CXR interpretation. Both prompt engineering and model parameter adjustments can play pivotal roles in interpreting CXRs.

Our approach, which we call Embeddings for Language/Image-aligned X-Rays, or ELIXR, leverages a language-aligned image encoder combined or grafted onto a fixed LLM, PaLM 2, to perform a broad range of tasks. We train this lightweight adapter architecture using images paired with corresponding free-text radiology reports from the MIMIC-CXR dataset. ELIXR achieved state-of-the-art performance on zero-shot chest X-ray (CXR) classification (mean AUC of 0.850 across 13 findings), data-efficient CXR classification (mean AUCs of 0.893 and 0.898 across five findings (atelectasis, cardiomegaly, consolidation, pleural effusion, and pulmonary edema) for 1% (~2,200 images) and 10% (~22,000 images) training data), and semantic search (0.76 normalized discounted cumulative gain (NDCG) across nineteen queries, including perfect retrieval on twelve of them). Compared to existing data-efficient methods including supervised contrastive learning (SupCon), ELIXR required two orders of magnitude less data to reach similar performance. ELIXR also showed promise on CXR vision-language tasks, demonstrating overall accuracies of 58.7% and 62.5% on visual question answering and report quality assurance tasks, respectively. These results suggest that ELIXR is a robust and versatile approach to CXR AI.

Radiology reports are crucial for planning treatment strategies and enhancing doctor-patient communication, yet manually writing these reports is burdensome for radiologists. While automatic report generation offers a solution, existing methods often rely on single-view radiographs, limiting diagnostic accuracy. To address this problem, we propose MCL, a Multi-view enhanced Contrastive Learning method for chest X-ray report generation. Specifically, we first introduce multi-view enhanced contrastive learning for visual representation by maximizing agreements between multi-view radiographs and their corresponding report. Subsequently, to fully exploit patient-specific indications (e.g., patient's symptoms) for report generation, we add a transitional ``bridge" for missing indications to reduce embedding space discrepancies caused by their presence or absence. Additionally, we construct Multi-view CXR and Two-view CXR datasets from public sources to support research on multi-view report generation. Our proposed MCL surpasses recent state-of-the-art methods across multiple datasets, achieving a 5.0% F1 RadGraph improvement on MIMIC-CXR, a 7.3% BLEU-1 improvement on MIMIC-ABN, a 3.1% BLEU-4 improvement on Multi-view CXR, and an 8.2% F1 CheXbert improvement on Two-view CXR.

Automated multi-label chest X-rays (CXR) image classification has achieved substantial progress in clinical diagnosis via utilizing sophisticated deep learning approaches. However, most deep models have high computational demands, which makes them less feasible for compact devices with low computational requirements. To overcome this problem, we propose a knowledge distillation (KD) strategy to create the compact deep learning model for the real-time multi-label CXR image classification. We study different alternatives of CNNs and Transforms as the teacher to distill the knowledge to a smaller student. Then, we employed explainable artificial intelligence (XAI) to provide the visual explanation for the model decision improved by the KD. Our results on three benchmark CXR datasets show that our KD strategy provides the improved performance on the compact student model, thus being the feasible choice for many limited hardware platforms. For instance, when using DenseNet161 as the teacher network, EEEA-Net-C2 achieved an AUC of 83.7%, 87.1%, and 88.7% on the ChestX-ray14, CheXpert, and PadChest datasets, respectively, with fewer parameters of 4.7 million and computational cost of 0.3 billion FLOPS.

Despite the progress in automatic detection of radiologic findings from chest X-ray (CXR) images in recent years, a quantitative evaluation of the explainability of these models is hampered by the lack of locally labeled datasets for different findings. With the exception of a few expert-labeled small-scale datasets for specific findings, such as pneumonia and pneumothorax, most of the CXR deep learning models to date are trained on global "weak" labels extracted from text reports, or trained via a joint image and unstructured text learning strategy. Inspired by the Visual Genome effort in the computer vision community, we constructed the first Chest ImaGenome dataset with a scene graph data structure to describe 242,072 images. Local annotations are automatically produced using a joint rule-based natural language processing (NLP) and atlas-based bounding box detection pipeline. Through a radiologist constructed CXR ontology, the annotations for each CXR are connected as an anatomy-centered scene graph, useful for image-level reasoning and multimodal fusion applications. Overall, we provide: i) 1,256 combinations of relation annotations between 29 CXR anatomical locations (objects with bounding box coordinates) and their attributes, structured as a scene graph per image, ii) over 670,000 localized comparison relations (for improved, worsened, or no change) between the anatomical locations across sequential exams, as well as ii) a manually annotated gold standard scene graph dataset from 500 unique patients.

This study investigates the integration of diverse patient data sources into multimodal language models for automated chest X-ray (CXR) report generation. Traditionally, CXR report generation relies solely on CXR images and limited radiology data, overlooking valuable information from patient health records, particularly from emergency departments. Utilising the MIMIC-CXR and MIMIC-IV-ED datasets, we incorporate detailed patient information such as aperiodic vital signs, medications, and clinical history to enhance diagnostic accuracy. We introduce a novel approach to transform these heterogeneous data sources into embeddings that prompt a multimodal language model, significantly enhancing the diagnostic accuracy of generated radiology reports. Our comprehensive evaluation demonstrates the benefits of using a broader set of patient data, underscoring the potential for enhanced diagnostic capabilities and better patient outcomes through the integration of multimodal data in CXR report generation.

The rapid evolution of artificial intelligence, especially in large language models (LLMs), has significantly impacted various domains, including healthcare. In chest X-ray (CXR) analysis, previous studies have employed LLMs, but with limitations: either underutilizing the multi-tasking capabilities of LLMs or lacking clinical accuracy. This paper presents M4CXR, a multi-modal LLM designed to enhance CXR interpretation. The model is trained on a visual instruction-following dataset that integrates various task-specific datasets in a conversational format. As a result, the model supports multiple tasks such as medical report generation (MRG), visual grounding, and visual question answering (VQA). M4CXR achieves state-of-the-art clinical accuracy in MRG by employing a chain-of-thought prompting strategy, in which it identifies findings in CXR images and subsequently generates corresponding reports. The model is adaptable to various MRG scenarios depending on the available inputs, such as single-image, multi-image, and multi-study contexts. In addition to MRG, M4CXR performs visual grounding at a level comparable to specialized models and also demonstrates outstanding performance in VQA. Both quantitative and qualitative assessments reveal M4CXR's versatility in MRG, visual grounding, and VQA, while consistently maintaining clinical accuracy.

Chest X-rays (CXRs) are among the most frequently performed imaging examinations worldwide, yet rising imaging volumes increase radiologist workload and the risk of diagnostic errors. Although artificial intelligence (AI) systems have shown promise for CXR interpretation, most generate only final predictions, without making explicit how visual evidence is translated into radiographic findings and diagnostic predictions. We present CheXOne, a reasoning-enabled vision-language model for CXR interpretation. CheXOne jointly generates diagnostic predictions and explicit, clinically grounded reasoning traces that connect visual evidence, radiographic findings, and these predictions. The model is trained on 14.7 million instruction and reasoning samples curated from 30 public datasets spanning 36 CXR interpretation tasks, using a two-stage framework that combines instruction tuning with reinforcement learning to improve reasoning quality. We evaluate CheXOne in zero-shot settings across visual question answering, report generation, visual grounding and reasoning assessment, covering 17 evaluation settings. CheXOne outperforms existing medical and general-domain foundation models and achieves strong performance on independent public benchmarks. A clinical reader study demonstrates that CheXOne-drafted reports are comparable to or better than resident-written reports in 55% of cases, while effectively addressing clinical indications and enhancing both report writing and CXR interpretation efficiency. Further analyses involving radiologists reveal that the generated reasoning traces show high clinical factuality and provide causal support for the final predictions, offering a plausible explanation for the performance gains. These results suggest that explicit reasoning can improve model performance, interpretability and clinical utility in AI-assisted CXR interpretation.

Chest radiography is an extremely powerful imaging modality, allowing for a detailed inspection of a patient's thorax, but requiring specialized training for proper interpretation. With the advent of high performance general purpose computer vision algorithms, the accurate automated analysis of chest radiographs is becoming increasingly of interest to researchers. However, a key challenge in the development of these techniques is the lack of sufficient data. Here we describe MIMIC-CXR-JPG v2.0.0, a large dataset of 377,110 chest x-rays associated with 227,827 imaging studies sourced from the Beth Israel Deaconess Medical Center between 2011 - 2016. Images are provided with 14 labels derived from two natural language processing tools applied to the corresponding free-text radiology reports. MIMIC-CXR-JPG is derived entirely from the MIMIC-CXR database, and aims to provide a convenient processed version of MIMIC-CXR, as well as to provide a standard reference for data splits and image labels. All images have been de-identified to protect patient privacy. The dataset is made freely available to facilitate and encourage a wide range of research in medical computer vision.

Chest X-ray (CXR) is the most frequently ordered imaging test, supporting diverse clinical tasks from thoracic disease detection to postoperative monitoring. However, task-specific classification models are limited in scope, require costly labeled data, and lack generalizability to out-of-distribution datasets. To address these challenges, we introduce CheXFound, a self-supervised vision foundation model that learns robust CXR representations and generalizes effectively across a wide range of downstream tasks. We pretrain CheXFound on a curated CXR-1M dataset, comprising over one million unique CXRs from publicly available sources. We propose a Global and Local Representations Integration (GLoRI) module for downstream adaptations, by incorporating disease-specific local features with global image features for enhanced performance in multilabel classification. Our experimental results show that CheXFound outperforms state-of-the-art models in classifying 40 disease findings across different prevalence levels on the CXR-LT 24 dataset and exhibits superior label efficiency on downstream tasks with limited training data. Additionally, CheXFound achieved significant improvements on new tasks with out-of-distribution datasets, including opportunistic cardiovascular disease risk estimation and mortality prediction. These results highlight CheXFound's strong generalization capabilities, enabling diverse adaptations with improved label efficiency. The project source code is publicly available at https://github.com/RPIDIAL/CheXFound.

Text-to-Image (T2I) models have recently seen notable progress around 1K and 2K resolution. With the extreme desire for better visual experience and the rapid development of imaging technology, the demand for Ultra-High-Resolution (UHR) image generation has grown significantly. However, UHR image generation poses great challenges due to the scarcity and complexity of high-resolution content. In this paper, we first introduce PixVerve-95K, a high-quality, open-source UHR T2I dataset curated with a carefully designed data pipeline, which contains 95K images across diverse scenarios (each image has a minimum pixel-count of 100M) and seven-dimensional annotations. Based on our large-scale image-text dataset, we take a pioneering step to extend various T2I foundation models to native 100MP generation with three training schemes. Finally, leveraging both conventional metrics and multimodal large language model-based assessments, our proposed PixVerve-Bench benchmark establishes a comprehensive evaluation protocol for UHR images encompassing visual quality and semantic alignment. Extensive experimental results on our benchmark and the constructive exploration of training strategies collaboratively provide valuable insights for future breakthroughs.

Automated radiology report generation offers an effective solution to alleviate radiologists' workload. However, most existing methods focus primarily on single or fixed-view images to model current disease conditions, which limits diagnostic accuracy and overlooks disease progression. Although some approaches utilize longitudinal data to track disease progression, they still rely on single images to analyze current visits. To address these issues, we propose enhanced contrastive learning with Multi-view Longitudinal data to facilitate chest X-ray Report Generation, named MLRG. Specifically, we introduce a multi-view longitudinal contrastive learning method that integrates spatial information from current multi-view images and temporal information from longitudinal data. This method also utilizes the inherent spatiotemporal information of radiology reports to supervise the pre-training of visual and textual representations. Subsequently, we present a tokenized absence encoding technique to flexibly handle missing patient-specific prior knowledge, allowing the model to produce more accurate radiology reports based on available prior knowledge. Extensive experiments on MIMIC-CXR, MIMIC-ABN, and Two-view CXR datasets demonstrate that our MLRG outperforms recent state-of-the-art methods, achieving a 2.3% BLEU-4 improvement on MIMIC-CXR, a 5.5% F1 score improvement on MIMIC-ABN, and a 2.7% F1 RadGraph improvement on Two-view CXR.

Chest X-ray (CXR) classification in clinical practice is often limited by imperfect supervision, arising from (i) extreme long-tailed multi-label disease distributions and (ii) missing annotations for rare or previously unseen findings. The CXR-LT 2026 challenge addresses these issues on a PadChest-based benchmark with a 36-class label space split into 30 in-distribution classes for training and 6 out-of-distribution (OOD) classes for zero-shot evaluation. We present task-specific solutions tailored to the distinct supervision regimes. For Task 1 (long-tailed multi-label classification), we adopt an imbalance-aware multi-label learning strategy to improve recognition of tail classes while maintaining stable performance on frequent findings. For Task 2 (zero-shot OOD recognition), we propose a prediction approach that produces scores for unseen disease categories without using any supervised labels or examples from the OOD classes during training. Evaluated with macro-averaged mean Average Precision (mAP), our method achieves strong performance on both tasks, ranking first on the public leaderboard of the development phase. Code and pre-trained models are available at https://github.com/hieuphamha19/CXR_LT.

Deep learning methods have shown outstanding classification accuracy in medical imaging problems, which is largely attributed to the availability of large-scale datasets manually annotated with clean labels. However, given the high cost of such manual annotation, new medical imaging classification problems may need to rely on machine-generated noisy labels extracted from radiology reports. Indeed, many Chest X-ray (CXR) classifiers have already been modelled from datasets with noisy labels, but their training procedure is in general not robust to noisy-label samples, leading to sub-optimal models. Furthermore, CXR datasets are mostly multi-label, so current noisy-label learning methods designed for multi-class problems cannot be easily adapted. In this paper, we propose a new method designed for the noisy multi-label CXR learning, which detects and smoothly re-labels samples from the dataset, which is then used to train common multi-label classifiers. The proposed method optimises a bag of multi-label descriptors (BoMD) to promote their similarity with the semantic descriptors produced by BERT models from the multi-label image annotation. Our experiments on diverse noisy multi-label training sets and clean testing sets show that our model has state-of-the-art accuracy and robustness in many CXR multi-label classification benchmarks.

High-resolution (HR) magnetic resonance imaging (MRI) is crucial for many clinical and research applications. However, achieving it remains costly and constrained by technical trade-offs and experimental limitations. Super-resolution (SR) presents a promising computational approach to overcome these challenges by generating HR images from more affordable low-resolution (LR) scans, potentially improving diagnostic accuracy and efficiency without requiring additional hardware. This survey reviews recent advances in MRI SR techniques, with a focus on deep learning (DL) approaches. It examines DL-based MRI SR methods from the perspectives of computer vision, computational imaging, inverse problems, and MR physics, covering theoretical foundations, architectural designs, learning strategies, benchmark datasets, and performance metrics. We propose a systematic taxonomy to categorize these methods and present an in-depth study of both established and emerging SR techniques applicable to MRI, considering unique challenges in clinical and research contexts. We also highlight open challenges and directions that the community needs to address. Additionally, we provide a collection of essential open-access resources, tools, and tutorials, available on our GitHub: https://github.com/mkhateri/Awesome-MRI-Super-Resolution. IEEE keywords: MRI, Super-Resolution, Deep Learning, Computational Imaging, Inverse Problem, Survey.

Automatic radiology report generation is a promising application of multimodal deep learning, aiming to reduce reporting workload and improve consistency. However, current state-of-the-art (SOTA) systems - such as Multimodal AI for Radiology Applications (MAIRA-2) and Medical Pathways Language Model-Multimodal (MedPaLM-M) - depend on large-scale multimodal training, clinical metadata, and multiple imaging views, making them resource-intensive and inaccessible for most settings. We introduce a compact image-to-text architecture that generates the Findings section of chest X-ray reports from a single frontal image. The model combines a frozen Self-Distillation with No Labels v3 (DINOv3) Vision Transformer (ViT) encoder with a Generative Pre-trained Transformer 2 (GPT-2) decoder enhanced by layer-wise anatomical attention. This mechanism integrates lung and heart segmentation masks through hierarchical Gaussian smoothing, biasing attention toward clinically relevant regions without adding trainable parameters. Evaluated on the official Medical Information Mart for Intensive Care-Chest X-ray (MIMIC-CXR) dataset using Chest Radiograph Expert (CheXpert) and Radiology Graph (RadGraph) metrics, our approach achieved substantial gains: CheXpert Macro-F1 for five key pathologies increased by 168% (0.083 -> 0.238) and Micro-F1 by 146% (0.137 -> 0.337), while broader performance across 14 observations improved by 86% (0.170 -> 0.316). Structural coherence also improved, with RadGraph F1 rising by 9.7%. Despite its small size and purely image-conditioned design, the model demonstrates that decoder-level anatomical guidance improves spatial grounding and enhances coherence in clinically relevant regions. The source code is publicly available at: https://github.com/devMuniz02/UDEM-CXR-Reporting-Thesis-2025.

Recently, several models based on deep neural networks have achieved great success in terms of both reconstruction accuracy and computational performance for single image super-resolution. In these methods, the low resolution (LR) input image is upscaled to the high resolution (HR) space using a single filter, commonly bicubic interpolation, before reconstruction. This means that the super-resolution (SR) operation is performed in HR space. We demonstrate that this is sub-optimal and adds computational complexity. In this paper, we present the first convolutional neural network (CNN) capable of real-time SR of 1080p videos on a single K2 GPU. To achieve this, we propose a novel CNN architecture where the feature maps are extracted in the LR space. In addition, we introduce an efficient sub-pixel convolution layer which learns an array of upscaling filters to upscale the final LR feature maps into the HR output. By doing so, we effectively replace the handcrafted bicubic filter in the SR pipeline with more complex upscaling filters specifically trained for each feature map, whilst also reducing the computational complexity of the overall SR operation. We evaluate the proposed approach using images and videos from publicly available datasets and show that it performs significantly better (+0.15dB on Images and +0.39dB on Videos) and is an order of magnitude faster than previous CNN-based methods.

Frontier models have demonstrated remarkable capabilities in understanding and reasoning with natural-language text, but they still exhibit major competency gaps in multimodal understanding and reasoning especially in high-value verticals such as biomedicine. Medical imaging report generation is a prominent example. Supervised fine-tuning can substantially improve performance, but they are prone to overfitting to superficial boilerplate patterns. In this paper, we introduce Universal Report Generation (UniRG) as a general framework for medical imaging report generation. By leveraging reinforcement learning as a unifying mechanism to directly optimize for evaluation metrics designed for end applications, UniRG can significantly improve upon supervised fine-tuning and attain durable generalization across diverse institutions and clinical practices. We trained UniRG-CXR on publicly available chest X-ray (CXR) data and conducted a thorough evaluation in CXR report generation with rigorous evaluation scenarios. On the authoritative ReXrank benchmark, UniRG-CXR sets new overall SOTA, outperforming prior state of the art by a wide margin.

Internal defect detection constitutes a critical process in ensuring component quality, for which anomaly detection serves as an effective solution. However, existing anomaly detection datasets predominantly focus on surface defects in visible-light images, lacking publicly available X-ray datasets targeting internal defects in components. To address this gap, we construct the first publicly accessible component X-ray anomaly detection (CXR-AD) dataset, comprising real-world X-ray images. The dataset covers five industrial component categories, including 653 normal samples and 561 defect samples with precise pixel-level mask annotations. We systematically analyze the dataset characteristics and identify three major technical challenges: (1) strong coupling between complex internal structures and defect regions, (2) inherent low contrast and high noise interference in X-ray imaging, and (3) significant variations in defect scales and morphologies. To evaluate dataset complexity, we benchmark three state-of-the-art anomaly detection frameworks (feature-based, reconstruction-based, and zero-shot learning methods). Experimental results demonstrate a 29.78% average performance degradation on CXR-AD compared to MVTec AD, highlighting the limitations of current algorithms in handling internal defect detection tasks. To the best of our knowledge, CXR-AD represents the first publicly available X-ray dataset for component anomaly detection, providing a real-world industrial benchmark to advance algorithm development and enhance precision in internal defect inspection technologies.

In this work we design an end-to-end deep learning architecture for predicting, on Chest X-rays images (CXR), a multi-regional score conveying the degree of lung compromise in COVID-19 patients. Such semi-quantitative scoring system, namely Brixia~score, is applied in serial monitoring of such patients, showing significant prognostic value, in one of the hospitals that experienced one of the highest pandemic peaks in Italy. To solve such a challenging visual task, we adopt a weakly supervised learning strategy structured to handle different tasks (segmentation, spatial alignment, and score estimation) trained with a "from-the-part-to-the-whole" procedure involving different datasets. In particular, we exploit a clinical dataset of almost 5,000 CXR annotated images collected in the same hospital. Our BS-Net demonstrates self-attentive behavior and a high degree of accuracy in all processing stages. Through inter-rater agreement tests and a gold standard comparison, we show that our solution outperforms single human annotators in rating accuracy and consistency, thus supporting the possibility of using this tool in contexts of computer-assisted monitoring. Highly resolved (super-pixel level) explainability maps are also generated, with an original technique, to visually help the understanding of the network activity on the lung areas. We also consider other scores proposed in literature and provide a comparison with a recently proposed non-specific approach. We eventually test the performance robustness of our model on an assorted public COVID-19 dataset, for which we also provide Brixia~score annotations, observing good direct generalization and fine-tuning capabilities that highlight the portability of BS-Net in other clinical settings. The CXR dataset along with the source code and the trained model are publicly released for research purposes.

With the advent of smart devices that support 4K and 8K resolution, Single Image Super Resolution (SISR) has become an important computer vision problem. However, most super resolution deep networks are computationally very expensive. In this paper, we propose Super-Efficient Super Resolution (SESR) networks that establish a new state-of-the-art for efficient super resolution. Our approach is based on linear overparameterization of CNNs and creates an efficient model architecture for SISR. With theoretical analysis, we uncover the limitations of existing overparameterization methods and show how the proposed method alleviates them. Detailed experiments across six benchmark datasets demonstrate that SESR achieves similar or better image quality than state-of-the-art models while requiring 2x to 330x fewer Multiply-Accumulate (MAC) operations. As a result, SESR can be used on constrained hardware to perform x2 (1080p to 4K) and x4 (1080p to 8K) SISR. Towards this, we estimate hardware performance numbers for a commercial Arm mobile-Neural Processing Unit (NPU) for 1080p to 4K (x2) and 1080p to 8K (x4) SISR. Our results highlight the challenges faced by super resolution on AI accelerators and demonstrate that SESR is significantly faster (e.g., 6x-8x higher FPS) than existing models on mobile-NPU. Finally, SESR outperforms prior models by 1.5x-2x in latency on Arm CPU and GPU when deployed on a real mobile device. The code for this work is available at https://github.com/ARM-software/sesr.

Multimodal models trained on large natural image-text pair datasets have exhibited astounding abilities in generating high-quality images. Medical imaging data is fundamentally different to natural images, and the language used to succinctly capture relevant details in medical data uses a different, narrow but semantically rich, domain-specific vocabulary. Not surprisingly, multi-modal models trained on natural image-text pairs do not tend to generalize well to the medical domain. Developing generative imaging models faithfully representing medical concepts while providing compositional diversity could mitigate the existing paucity of high-quality, annotated medical imaging datasets. In this work, we develop a strategy to overcome the large natural-medical distributional shift by adapting a pre-trained latent diffusion model on a corpus of publicly available chest x-rays (CXR) and their corresponding radiology (text) reports. We investigate the model's ability to generate high-fidelity, diverse synthetic CXR conditioned on text prompts. We assess the model outputs quantitatively using image quality metrics, and evaluate image quality and text-image alignment by human domain experts. We present evidence that the resulting model (RoentGen) is able to create visually convincing, diverse synthetic CXR images, and that the output can be controlled to a new extent by using free-form text prompts including radiology-specific language. Fine-tuning this model on a fixed training set and using it as a data augmentation method, we measure a 5% improvement of a classifier trained jointly on synthetic and real images, and a 3% improvement when trained on a larger but purely synthetic training set. Finally, we observe that this fine-tuning distills in-domain knowledge in the text-encoder and can improve its representation capabilities of certain diseases like pneumothorax by 25%.

Recent research on super-resolution has progressed with the development of deep convolutional neural networks (DCNN). In particular, residual learning techniques exhibit improved performance. In this paper, we develop an enhanced deep super-resolution network (EDSR) with performance exceeding those of current state-of-the-art SR methods. The significant performance improvement of our model is due to optimization by removing unnecessary modules in conventional residual networks. The performance is further improved by expanding the model size while we stabilize the training procedure. We also propose a new multi-scale deep super-resolution system (MDSR) and training method, which can reconstruct high-resolution images of different upscaling factors in a single model. The proposed methods show superior performance over the state-of-the-art methods on benchmark datasets and prove its excellence by winning the NTIRE2017 Super-Resolution Challenge.

Super-resolution (SR) advances astronomical imaging by enabling cost-effective high-resolution capture, crucial for detecting faraway celestial objects and precise structural analysis. However, existing datasets for astronomical SR (ASR) exhibit three critical limitations: flux inconsistency, object-crop setting, and insufficient data diversity, significantly impeding ASR development. We propose STAR, a large-scale astronomical SR dataset containing 54,738 flux-consistent star field image pairs covering wide celestial regions. These pairs combine Hubble Space Telescope high-resolution observations with physically faithful low-resolution counterparts generated through a flux-preserving data generation pipeline, enabling systematic development of field-level ASR models. To further empower the ASR community, STAR provides a novel Flux Error (FE) to evaluate SR models in physical view. Leveraging this benchmark, we propose a Flux-Invariant Super Resolution (FISR) model that could accurately infer the flux-consistent high-resolution images from input photometry, suppressing several SR state-of-the-art methods by 24.84% on a novel designed flux consistency metric, showing the priority of our method for astrophysics. Extensive experiments demonstrate the effectiveness of our proposed method and the value of our dataset. Code and models are available at https://github.com/GuoCheng12/STAR.

Chest X-ray (CXR) radiology report generation (RRG) models have shown rapid progress, yet their clinical utility remains uncertain due to limited evaluation by radiologists. We present CXRMate-2, a state-of-the-art CXR RRG model that integrates structured multimodal conditioning and reinforcement learning with a composite reward for semantic alignment with radiologist reports. Across the MIMIC-CXR, CheXpert Plus, and ReXgradient datasets, CXRMate-2 achieves statistically significant improvements over strong benchmarks, including gains of 11.2% and 24.4% in GREEN and RadGraph-XL, respectively, on MIMIC-CXR relative to MedGemma 1.5 (4B). To directly compare CXRMate-2 against radiologist reporting, we conduct a blinded, randomised qualitative retrospective evaluation. Three consultant radiologists compare generated and radiologist reports across 120 studies from the MIMIC-CXR test set. Generated reports were deemed acceptable (defined as preferred or rated equally to radiologist reports) in 45% of ratings, with no statistically significant difference in preference rates between radiologist reports and acceptable generated reports for seven of the eight analysed findings. Preference for radiologist reports was driven primarily by higher recall, while generated reports were often preferred for readability. Together, these results suggest a credible pathway to clinically acceptable CXR RRG. Improvements in recall, alongside better detection of subtle findings (e.g., pulmonary congestion), are likely sufficient to achieve non-inferiority to radiologist reporting. With these targeted advances, CXR RRG systems may be ready for prospective evaluation in assistive roles within radiologist-led workflows.

Longitudinal chest X-ray (CXR) interpretation requires reasoning over disease evolution across multiple patient visits, yet most existing medical VQA benchmarks focus on single images or short-horizon image pairs. We introduce MI-CXR, a benchmark for standardized evaluation of Multi-Interval longitudinal reasoning over multi-visit CXR sequences, without requiring free-form report generation or additional clinical context. MI-CXR comprises five-way multiple-choice questions over five-visit patient timelines and instantiates three complementary task families: Temporal Event Localization, Interval-wise Change Reasoning, and Global Trajectory Summarization, which assess clinically grounded visual reasoning over time. Evaluating 14 state-of-the-art vision-language models (VLMs) shows low overall performance, with an average accuracy of 29.3%, only modestly above random guessing. Using stage-wise diagnostic probing, we find that models often produce locally plausible interval descriptions but fail to enforce temporal constraints or compose evidence into globally consistent decisions over the full timeline. These findings reveal key limitations of current VLMs and establish MI-CXR as a principled benchmark for longitudinal medical reasoning. The benchmark is available at https://github.com/AIDASLab/MI-CXR

Chest Xray imaging is a widely used diagnostic tool in modern medicine, and its high utilization creates substantial workloads for radiologists. To alleviate this burden, vision language models are increasingly applied to automate Chest Xray radiology report generation (CXRRRG), aiming for clinically accurate descriptions while reducing manual effort. Conventional approaches, however, typically rely on single images, failing to capture the longitudinal context necessary for producing clinically faithful comparison statements. Recently, growing attention has been directed toward incorporating longitudinal data into CXR RRG, enabling models to leverage historical studies in ways that mirror radiologists diagnostic workflows. Nevertheless, existing surveys primarily address single image CXRRRG and offer limited guidance for longitudinal settings, leaving researchers without a systematic framework for model design. To address this gap, this survey provides the first comprehensive review of longitudinal radiology report generation (LRRG). Specifically, we examine dataset construction strategies, report generation architectures alongside longitudinally tailored designs, and evaluation protocols encompassing both longitudinal specific measures and widely used benchmarks. We further summarize LRRG methods performance, alongside analyses of different ablation studies, which collectively highlight the critical role of longitudinal information and architectural design choices in improving model performance. Finally, we summarize five major limitations of current research and outline promising directions for future development, aiming to lay a foundation for advancing this emerging field.

This paper proposes a novel framework for lung segmentation in chest X-rays. It consists of two key contributions, a criss-cross attention based segmentation network and radiorealistic chest X-ray image synthesis (i.e. a synthesized radiograph that appears anatomically realistic) for data augmentation. The criss-cross attention modules capture rich global contextual information in both horizontal and vertical directions for all the pixels thus facilitating accurate lung segmentation. To reduce the manual annotation burden and to train a robust lung segmentor that can be adapted to pathological lungs with hazy lung boundaries, an image-to-image translation module is employed to synthesize radiorealistic abnormal CXRs from the source of normal ones for data augmentation. The lung masks of synthetic abnormal CXRs are propagated from the segmentation results of their normal counterparts, and then serve as pseudo masks for robust segmentor training. In addition, we annotate 100 CXRs with lung masks on a more challenging NIH Chest X-ray dataset containing both posterioranterior and anteroposterior views for evaluation. Extensive experiments validate the robustness and effectiveness of the proposed framework. The code and data can be found from https://github.com/rsummers11/CADLab/tree/master/Lung_Segmentation_XLSor .

Medical image synthesis presents unique challenges due to the inherent complexity and high-resolution details required in clinical contexts. Traditional generative architectures such as Generative Adversarial Networks (GANs) or Variational Auto Encoder (VAEs) have shown great promise for high-resolution image generation but struggle with preserving fine-grained details that are key for accurate diagnosis. To address this issue, we introduce Pixel Perfect MegaMed, the first vision-language foundation model to synthesize images at resolutions of 1024x1024. Our method deploys a multi-scale transformer architecture designed specifically for ultra-high resolution medical image generation, enabling the preservation of both global anatomical context and local image-level details. By leveraging vision-language alignment techniques tailored to medical terminology and imaging modalities, Pixel Perfect MegaMed bridges the gap between textual descriptions and visual representations at unprecedented resolution levels. We apply our model to the CheXpert dataset and demonstrate its ability to generate clinically faithful chest X-rays from text prompts. Beyond visual quality, these high-resolution synthetic images prove valuable for downstream tasks such as classification, showing measurable performance gains when used for data augmentation, particularly in low-data regimes. Our code is accessible through the project website - https://tehraninasab.github.io/pixelperfect-megamed.

We present a radiology-specific multimodal model for the task for generating radiological reports from chest X-rays (CXRs). Our work builds on the idea that large language model(s) can be equipped with multimodal capabilities through alignment with pre-trained vision encoders. On natural images, this has been shown to allow multimodal models to gain image understanding and description capabilities. Our proposed model (MAIRA-1) leverages a CXR-specific image encoder in conjunction with a fine-tuned large language model based on Vicuna-7B, and text-based data augmentation, to produce reports with state-of-the-art quality. In particular, MAIRA-1 significantly improves on the radiologist-aligned RadCliQ metric and across all lexical metrics considered. Manual review of model outputs demonstrates promising fluency and accuracy of generated reports while uncovering failure modes not captured by existing evaluation practices. More information and resources can be found on the project website: https://aka.ms/maira.

3D super-resolution aims to reconstruct high-fidelity 3D models from low-resolution (LR) multi-view images. Early studies primarily focused on single-image super-resolution (SISR) models to upsample LR images into high-resolution images. However, these methods often lack view consistency because they operate independently on each image. Although various post-processing techniques have been extensively explored to mitigate these inconsistencies, they have yet to fully resolve the issues. In this paper, we perform a comprehensive study of 3D super-resolution by leveraging video super-resolution (VSR) models. By utilizing VSR models, we ensure a higher degree of spatial consistency and can reference surrounding spatial information, leading to more accurate and detailed reconstructions. Our findings reveal that VSR models can perform remarkably well even on sequences that lack precise spatial alignment. Given this observation, we propose a simple yet practical approach to align LR images without involving fine-tuning or generating 'smooth' trajectory from the trained 3D models over LR images. The experimental results show that the surprisingly simple algorithms can achieve the state-of-the-art results of 3D super-resolution tasks on standard benchmark datasets, such as the NeRF-synthetic and MipNeRF-360 datasets. Project page: https://ko-lani.github.io/Sequence-Matters

Integrating multi-modal clinical data, such as electronic health records (EHR) and chest X-ray images (CXR), is particularly beneficial for clinical prediction tasks. However, in a temporal setting, multi-modal data are often inherently asynchronous. EHR can be continuously collected but CXR is generally taken with a much longer interval due to its high cost and radiation dose. When clinical prediction is needed, the last available CXR image might have been outdated, leading to suboptimal predictions. To address this challenge, we propose DDL-CXR, a method that dynamically generates an up-to-date latent representation of the individualized CXR images. Our approach leverages latent diffusion models for patient-specific generation strategically conditioned on a previous CXR image and EHR time series, providing information regarding anatomical structures and disease progressions, respectively. In this way, the interaction across modalities could be better captured by the latent CXR generation process, ultimately improving the prediction performance. Experiments using MIMIC datasets show that the proposed model could effectively address asynchronicity in multimodal fusion and consistently outperform existing methods.

We present VinDr-CXR-VQA, a large-scale chest X-ray dataset for explainable Medical Visual Question Answering (Med-VQA) with spatial grounding. The dataset contains 17,597 question-answer pairs across 4,394 images, each annotated with radiologist-verified bounding boxes and clinical reasoning explanations. Our question taxonomy spans six diagnostic types-Where, What, Is there, How many, Which, and Yes/No-capturing diverse clinical intents. To improve reliability, we construct a balanced distribution of 41.7% positive and 58.3% negative samples, mitigating hallucinations in normal cases. Benchmarking with MedGemma-4B-it demonstrates improved performance (F1 = 0.624, +11.8% over baseline) while enabling lesion localization. VinDr-CXR-VQA aims to advance reproducible and clinically grounded Med-VQA research. The dataset and evaluation tools are publicly available at huggingface.co/datasets/Dangindev/VinDR-CXR-VQA.

Chest X-rays (CXRs) play an integral role in driving critical decisions in disease management and patient care. While recent innovations have led to specialized models for various CXR interpretation tasks, these solutions often operate in isolation, limiting their practical utility in clinical practice. We present MedRAX, the first versatile AI agent that seamlessly integrates state-of-the-art CXR analysis tools and multimodal large language models into a unified framework. MedRAX dynamically leverages these models to address complex medical queries without requiring additional training. To rigorously evaluate its capabilities, we introduce ChestAgentBench, a comprehensive benchmark containing 2,500 complex medical queries across 7 diverse categories. Our experiments demonstrate that MedRAX achieves state-of-the-art performance compared to both open-source and proprietary models, representing a significant step toward the practical deployment of automated CXR interpretation systems. Data and code have been publicly available at https://github.com/bowang-lab/MedRAX

The evaluation of vision-language models (VLMs) for chest X-ray (CXR) analysis has largely been limited to disease-presence classification without visual grounding. Such evaluations fail to verify the expert-level lesion perception necessary to ensure the clinical reliability of VLMs. To address these limitations, we introduce CheXpercept, a sequential, multi-level perception benchmark that mirrors a radiologist's cognitive workflow across coarse-level detection, fine-level contour evaluation and revision, and semantic-level attribute extraction. To ensure high clinical fidelity at scale, we construct the dataset using a semi-automated generation pipeline paired with a review by six medical experts. CheXpercept contains 10,400 QA items derived from 2,100 CXRs, covering seven clinically critical pulmonary and cardiac lesions. To demonstrate the current landscape of VLM perception, we benchmark 14 general and medical VLMs on CheXpercept. The models achieve adequate performance only at the coarse level, with accuracy degrading precipitously on deeper visual tasks. Notably, medical VLMs show almost no perceptual advantage over their general-domain counterparts, highlighting a systemic flaw in current domain adaptation. The code and dataset will be publicly available.

Chest X-ray (CXR) segmentation is an important step in computer-aided diagnosis, yet deploying large foundation models in clinical settings remains challenging due to computational constraints. We propose AdaLoRA-QAT, a two-stage fine-tuning framework that combines adaptive low-rank encoder adaptation with full quantization-aware training. Adaptive rank allocation improves parameter efficiency, while selective mixed-precision INT8 quantization preserves structural fidelity crucial for clinical reliability. Evaluated across large-scale CXR datasets, AdaLoRA-QAT achieves 95.6% Dice, matching full-precision SAM decoder fine-tuning while reducing trainable parameters by 16.6\times and yielding 2.24\times model compression. A Wilcoxon signed-rank test confirms that quantization does not significantly degrade segmentation accuracy. These results demonstrate that AdaLoRA-QAT effectively balances accuracy, efficiency, and structural trust-worthiness, enabling compact and deployable foundation models for medical image segmentation. Code and pretrained models are available at: https://prantik-pdeb.github.io/adaloraqat.github.io/

As a successful deep model applied in image super-resolution (SR), the Super-Resolution Convolutional Neural Network (SRCNN) has demonstrated superior performance to the previous hand-crafted models either in speed and restoration quality. However, the high computational cost still hinders it from practical usage that demands real-time performance (24 fps). In this paper, we aim at accelerating the current SRCNN, and propose a compact hourglass-shape CNN structure for faster and better SR. We re-design the SRCNN structure mainly in three aspects. First, we introduce a deconvolution layer at the end of the network, then the mapping is learned directly from the original low-resolution image (without interpolation) to the high-resolution one. Second, we reformulate the mapping layer by shrinking the input feature dimension before mapping and expanding back afterwards. Third, we adopt smaller filter sizes but more mapping layers. The proposed model achieves a speed up of more than 40 times with even superior restoration quality. Further, we present the parameter settings that can achieve real-time performance on a generic CPU while still maintaining good performance. A corresponding transfer strategy is also proposed for fast training and testing across different upscaling factors.

Long-tailed class distributions pose a significant challenge for multi-label chest X-ray (CXR) classification, where rare but clinically important findings are severely underrepresented. In this work, we present a systematic empirical evaluation of loss functions, CNN backbone architectures and post-training strategies on the CXR-LT 2026 benchmark, comprising approximately 143K images with 30 disease labels from PadChest. Our experiments demonstrate that LDAM with deferred re-weighting (LDAM-DRW) consistently outperforms standard BCE and asymmetric losses for rare class recognition. Amongst the architectures evaluated, ConvNeXt-Large achieves the best single-model performance with 0.5220 mAP and 0.3765 F1 on our development set, whilst classifier re-training and test-time augmentation further improve ranking metrics. On the official test leaderboard, our submission achieved 0.3950 mAP, ranking 5th amongst all 68 participating teams with total of 1528 submissions. We provide a candid analysis of the development-to-test performance gap and discuss practical insights for handling class imbalance in clinical imaging settings. Code is available at https://github.com/Nikhil-Rao20/Long_Tail.

Despite the success of Large Language Models (LLMs) in general image tasks, a gap persists in the medical field for a multimodal large model adept at handling the nuanced diversity of medical images. Addressing this, we propose MedXChat, a unified multimodal large model designed for seamless interactions between medical assistants and users. MedXChat encompasses three key functionalities: CXR(Chest X-ray)-to-Report generation, CXR-based visual question-answering (VQA), and Text-to-CXR synthesis. Our contributions are as follows. Firstly, our model showcases exceptional cross-task adaptability, displaying adeptness across all three defined tasks and outperforming the benchmark models on the MIMIC dataset in medical multimodal applications. Secondly, we introduce an innovative Text-to-CXR synthesis approach that utilizes instruction-following capabilities within the Stable Diffusion (SD) architecture. This technique integrates smoothly with the existing model framework, requiring no extra parameters, thereby maintaining the SD's generative strength while also bestowing upon it the capacity to render fine-grained medical images with high fidelity. Comprehensive experiments validate MedXChat's synergistic enhancement across all tasks. Our instruction data and model will be open-sourced.

This paper presents a comprehensive review of the NTIRE 2025 Challenge on Single-Image Efficient Super-Resolution (ESR). The challenge aimed to advance the development of deep models that optimize key computational metrics, i.e., runtime, parameters, and FLOPs, while achieving a PSNR of at least 26.90 dB on the DIV2K_LSDIR_valid dataset and 26.99 dB on the DIV2K_LSDIR_test dataset. A robust participation saw 244 registered entrants, with 43 teams submitting valid entries. This report meticulously analyzes these methods and results, emphasizing groundbreaking advancements in state-of-the-art single-image ESR techniques. The analysis highlights innovative approaches and establishes benchmarks for future research in the field.

Synthetic medical data generation has opened up new possibilities in the healthcare domain, offering a powerful tool for simulating clinical scenarios, enhancing diagnostic and treatment quality, gaining granular medical knowledge, and accelerating the development of unbiased algorithms. In this context, we present a novel approach called ViewXGen, designed to overcome the limitations of existing methods that rely on general domain pipelines using only radiology reports to generate frontal-view chest X-rays. Our approach takes into consideration the diverse view positions found in the dataset, enabling the generation of chest X-rays with specific views, which marks a significant advancement in the field. To achieve this, we introduce a set of specially designed tokens for each view position, tailoring the generation process to the user's preferences. Furthermore, we leverage multi-view chest X-rays as input, incorporating valuable information from different views within the same study. This integration rectifies potential errors and contributes to faithfully capturing abnormal findings in chest X-ray generation. To validate the effectiveness of our approach, we conducted statistical analyses, evaluating its performance in a clinical efficacy metric on the MIMIC-CXR dataset. Also, human evaluation demonstrates the remarkable capabilities of ViewXGen, particularly in producing realistic view-specific X-rays that closely resemble the original images.

Real-world image super-resolution is a critical image processing task, where two key evaluation criteria are the fidelity to the original image and the visual realness of the generated results. Although existing methods based on diffusion models excel in visual realness by leveraging strong priors, they often struggle to achieve an effective balance between fidelity and realness. In our preliminary experiments, we observe that a linear combination of multiple models outperforms individual models, motivating us to harness the strengths of different models for a more effective trade-off. Based on this insight, we propose a distillation-based approach that leverages the geometric decomposition of both fidelity and realness, alongside the performance advantages of multiple teacher models, to strike a more balanced trade-off. Furthermore, we explore the controllability of this trade-off, enabling a flexible and adjustable super-resolution process, which we call CTSR (Controllable Trade-off Super-Resolution). Experiments conducted on several real-world image super-resolution benchmarks demonstrate that our method surpasses existing state-of-the-art approaches, achieving superior performance across both fidelity and realness metrics.

Diffusion-based methods, endowed with a formidable generative prior, have received increasing attention in Image Super-Resolution (ISR) recently. However, as low-resolution (LR) images often undergo severe degradation, it is challenging for ISR models to perceive the semantic and degradation information, resulting in restoration images with incorrect content or unrealistic artifacts. To address these issues, we propose a Cross-modal Priors for Super-Resolution (XPSR) framework. Within XPSR, to acquire precise and comprehensive semantic conditions for the diffusion model, cutting-edge Multimodal Large Language Models (MLLMs) are utilized. To facilitate better fusion of cross-modal priors, a Semantic-Fusion Attention is raised. To distill semantic-preserved information instead of undesired degradations, a Degradation-Free Constraint is attached between LR and its high-resolution (HR) counterpart. Quantitative and qualitative results show that XPSR is capable of generating high-fidelity and high-realism images across synthetic and real-world datasets. Codes are released at https://github.com/qyp2000/XPSR.

Super resolution techniques can enhance the spatial resolution of remote sensing images, enabling more efficient large scale earth observation applications. While single image SR methods enhance low resolution images, they neglect valuable complementary information from auxiliary data. Reference based SR can be interpreted as an information fusion task, where historical high resolution reference images are combined with current LR observations. However, existing RefSR methods struggle with real world complexities, such as cross sensor resolution gap and significant land cover changes, often leading to under generation or over reliance on reference image. To address these challenges, we propose CRefDiff, a novel controllable reference guided diffusion model for real world remote sensing image SR. To address the under generation problem, CRefDiff leverages a powerful generative prior to produce accurate structures and textures. To mitigate over reliance on the reference, we introduce a dual branch fusion mechanism that adaptively fuse both local and global information from the reference image. Moreover, the dual branch design enables reference strength control during inference, enhancing the models interactivity and flexibility. Finally, the Better Start strategy is proposed to significantly reduce the number of denoising steps, thereby accelerating the inference process. To support further research, we introduce RealRefRSSRD, a new real world RefSR dataset for remote sensing images, consisting of HR NAIP and LR Sentinel2 image pairs with diverse land cover changes and significant temporal gaps. Extensive experiments on RealRefRSSRD show that CRefDiff achieves SOTA performance and improves downstream tasks.

Great successes have been achieved using deep learning techniques for image super-resolution (SR) with fixed scales. To increase its real world applicability, numerous models have also been proposed to restore SR images with arbitrary scale factors, including asymmetric ones where images are resized to different scales along horizontal and vertical directions. Though most models are only optimized for the unidirectional upscaling task while assuming a predefined downscaling kernel for low-resolution (LR) inputs, recent models based on Invertible Neural Networks (INN) are able to increase upscaling accuracy significantly by optimizing the downscaling and upscaling cycle jointly. However, limited by the INN architecture, it is constrained to fixed integer scale factors and requires one model for each scale. Without increasing model complexity, a simple and effective invertible arbitrary rescaling network (IARN) is proposed to achieve arbitrary image rescaling by training only one model in this work. Using innovative components like position-aware scale encoding and preemptive channel splitting, the network is optimized to convert the non-invertible rescaling cycle to an effectively invertible process. It is shown to achieve a state-of-the-art (SOTA) performance in bidirectional arbitrary rescaling without compromising perceptual quality in LR outputs. It is also demonstrated to perform well on tests with asymmetric scales using the same network architecture.

Real-world Super-Resolution (Real-SR) methods focus on dealing with diverse real-world images and have attracted increasing attention in recent years. The key idea is to use a complex and high-order degradation model to mimic real-world degradations. Although they have achieved impressive results in various scenarios, they are faced with the obstacle of evaluation. Currently, these methods are only assessed by their average performance on a small set of degradation cases randomly selected from a large space, which fails to provide a comprehensive understanding of their overall performance and often yields inconsistent and potentially misleading results. To overcome the limitation in evaluation, we propose SEAL, a framework for systematic evaluation of real-SR. In particular, we cluster the extensive degradation space to create a set of representative degradation cases, which serves as a comprehensive test set. Next, we propose a coarse-to-fine evaluation protocol to measure the distributed and relative performance of real-SR methods on the test set. The protocol incorporates two new metrics: acceptance rate (AR) and relative performance ratio (RPR), derived from acceptance and excellence lines. Under SEAL, we benchmark existing real-SR methods, obtain new observations and insights into their performance, and develop a new strong baseline. We consider SEAL as the first step towards creating a comprehensive real-SR evaluation platform, which can promote the development of real-SR. The source code is available at https://github.com/XPixelGroup/SEAL

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because medical image analysis and generation consist of reasoning based on a combination of visual features and prior knowledge. Many recent works have focused on training adapter networks that serve as an information bridge between image processing networks and LLMs; but presumably, in order to achieve maximum reasoning potential of LLMs on visual information as well, visual and language features should be allowed to interact more freely. This is especially important in the medical domain because understanding and generating medical images such as chest X-rays (CXR) require not only accurate visual and language-based reasoning but also a more intimate mapping between the two modalities. Thus, taking inspiration from previous work on the transformer and VQ-GAN combination for bidirectional image and text generation, we build upon this approach and develop a method for instruction-tuning an LLM pre-trained only on text to gain vision-language capabilities for medical images. Specifically, we leverage a pretrained LLM's existing question-answering and instruction-following abilities to teach it to understand visual inputs by instructing it to answer questions about image inputs and, symmetrically, output both text and image responses appropriate to a given query by tuning the LLM with diverse tasks that encompass image-based text-generation and text-based image-generation. We show that our model, LLM-CXR, trained in this approach shows better image-text alignment in both CXR understanding and generation tasks while being smaller in size compared to previously developed models that perform a narrower range of tasks. The code is at https://github.com/hyn2028/llm-cxr.

Longitudinal multimodal data, including electronic health records (EHR) and sequential chest X-rays (CXRs), is critical for modeling disease progression, yet remains underutilized due to two key challenges: (1) redundancy in consecutive CXR sequences, where static anatomical regions dominate over clinically-meaningful dynamics, and (2) temporal misalignment between sparse, irregular imaging and continuous EHR data. We introduce DiPro, a novel framework that addresses these challenges through region-aware disentanglement and multi-timescale alignment. First, we disentangle static (anatomy) and dynamic (pathology progression) features in sequential CXRs, prioritizing disease-relevant changes. Second, we hierarchically align these static and dynamic CXR features with asynchronous EHR data via local (pairwise interval-level) and global (full-sequence) synchronization to model coherent progression pathways. Extensive experiments on the MIMIC dataset demonstrate that DiPro could effectively extract temporal clinical dynamics and achieve state-of-the-art performance on both disease progression identification and general ICU prediction tasks.

Medical image arbitrary-scale super-resolution (MIASSR) has recently gained widespread attention, aiming to super sample medical volumes at arbitrary scales via a single model. However, existing MIASSR methods face two major limitations: (i) reliance on high-resolution (HR) volumes and (ii) limited generalization ability, which restricts their application in various scenarios. To overcome these limitations, we propose Cube-based Neural Radiance Field (CuNeRF), a zero-shot MIASSR framework that can yield medical images at arbitrary scales and viewpoints in a continuous domain. Unlike existing MIASSR methods that fit the mapping between low-resolution (LR) and HR volumes, CuNeRF focuses on building a coordinate-intensity continuous representation from LR volumes without the need for HR references. This is achieved by the proposed differentiable modules: including cube-based sampling, isotropic volume rendering, and cube-based hierarchical rendering. Through extensive experiments on magnetic resource imaging (MRI) and computed tomography (CT) modalities, we demonstrate that CuNeRF outperforms state-of-the-art MIASSR methods. CuNeRF yields better visual verisimilitude and reduces aliasing artifacts at various upsampling factors. Moreover, our CuNeRF does not need any LR-HR training pairs, which is more flexible and easier to be used than others. Our code will be publicly available soon.

High Content Screening (HCS) microscopy datasets have transformed the ability to profile cellular responses to genetic and chemical perturbations, enabling cell-based inference of drug-target interactions (DTI). However, the adoption of representation learning methods for HCS data has been hindered by the lack of accessible datasets and robust benchmarks. To address this gap, we present RxRx3-core, a curated and compressed subset of the RxRx3 dataset, and an associated DTI benchmarking task. At just 18GB, RxRx3-core significantly reduces the size barrier associated with large-scale HCS datasets while preserving critical data necessary for benchmarking representation learning models against a zero-shot DTI prediction task. RxRx3-core includes 222,601 microscopy images spanning 736 CRISPR knockouts and 1,674 compounds at 8 concentrations. RxRx3-core is available on HuggingFace and Polaris, along with pre-trained embeddings and benchmarking code, ensuring accessibility for the research community. By providing a compact dataset and robust benchmarks, we aim to accelerate innovation in representation learning methods for HCS data and support the discovery of novel biological insights.

In recent times, the need for effective super-resolution (SR) techniques has surged, especially for large-scale images ranging 2K to 8K resolutions. For DNN-based SISR, decomposing images into overlapping patches is typically necessary due to computational constraints. In such patch-decomposing scheme, one can allocate computational resources differently based on each patch's difficulty to further improve efficiency while maintaining SR performance. However, this approach has a limitation: computational resources is uniformly allocated within a patch, leading to lower efficiency when the patch contain pixels with varying levels of restoration difficulty. To address the issue, we propose the Pixel-level Classifier for Single Image Super-Resolution (PCSR), a novel method designed to distribute computational resources adaptively at the pixel level. A PCSR model comprises a backbone, a pixel-level classifier, and a set of pixel-level upsamplers with varying capacities. The pixel-level classifier assigns each pixel to an appropriate upsampler based on its restoration difficulty, thereby optimizing computational resource usage. Our method allows for performance and computational cost balance during inference without re-training. Our experiments demonstrate PCSR's advantage over existing patch-distributing methods in PSNR-FLOP trade-offs across different backbone models and benchmarks. The code is available at https://github.com/3587jjh/PCSR.

Vision-language pretraining has advanced image-text alignment, yet progress in radiology remains constrained by the heterogeneity of clinical reports, including abbreviations, impression-only notes, and stylistic variability. Unlike general-domain settings where more data often leads to better performance, naively scaling to large collections of noisy reports can plateau or even degrade model learning. We ask whether large language model (LLM) encoders can provide robust clinical representations that transfer across diverse styles and better guide image-text alignment. We introduce LLM2VEC4CXR, a domain-adapted LLM encoder for chest X-ray reports, and LLM2CLIP4CXR, a dual-tower framework that couples this encoder with a vision backbone. LLM2VEC4CXR improves clinical text understanding over BERT-based baselines, handles abbreviations and style variation, and achieves strong clinical alignment on report-level metrics. LLM2CLIP4CXR leverages these embeddings to boost retrieval accuracy and clinically oriented scores, with stronger cross-dataset generalization than prior medical CLIP variants. Trained on 1.6M CXR studies from public and private sources with heterogeneous and noisy reports, our models demonstrate that robustness -- not scale alone -- is the key to effective multimodal learning. We release models to support further research in medical image-text representation learning.

Existing super-resolution (SR) models primarily focus on restoring local texture details, often neglecting the global semantic information within the scene. This oversight can lead to the omission of crucial semantic details or the introduction of inaccurate textures during the recovery process. In our work, we introduce the Cognitive Super-Resolution (CoSeR) framework, empowering SR models with the capacity to comprehend low-resolution images. We achieve this by marrying image appearance and language understanding to generate a cognitive embedding, which not only activates prior information from large text-to-image diffusion models but also facilitates the generation of high-quality reference images to optimize the SR process. To further improve image fidelity, we propose a novel condition injection scheme called "All-in-Attention", consolidating all conditional information into a single module. Consequently, our method successfully restores semantically correct and photorealistic details, demonstrating state-of-the-art performance across multiple benchmarks. Code: https://github.com/VINHYU/CoSeR

Chest X-rays (CXR) are the most common medical imaging study and are used to diagnose multiple medical conditions. This study examines the impact of synthetic data supplementation, using diffusion models, on the performance of deep learning (DL) classifiers for CXR analysis. We employed three datasets: CheXpert, MIMIC-CXR, and Emory Chest X-ray, training conditional denoising diffusion probabilistic models (DDPMs) to generate synthetic frontal radiographs. Our approach ensured that synthetic images mirrored the demographic and pathological traits of the original data. Evaluating the classifiers' performance on internal and external datasets revealed that synthetic data supplementation enhances model accuracy, particularly in detecting less prevalent pathologies. Furthermore, models trained on synthetic data alone approached the performance of those trained on real data. This suggests that synthetic data can potentially compensate for real data shortages in training robust DL models. However, despite promising outcomes, the superiority of real data persists.

In this paper, we introduce DRR-RATE, a large-scale synthetic chest X-ray dataset derived from the recently released CT-RATE dataset. DRR-RATE comprises of 50,188 frontal Digitally Reconstructed Radiographs (DRRs) from 21,304 unique patients. Each image is paired with a corresponding radiology text report and binary labels for 18 pathology classes. Given the controllable nature of DRR generation, it facilitates the inclusion of lateral view images and images from any desired viewing position. This opens up avenues for research into new and novel multimodal applications involving paired CT, X-ray images from various views, text, and binary labels. We demonstrate the applicability of DRR-RATE alongside existing large-scale chest X-ray resources, notably the CheXpert dataset and CheXnet model. Experiments demonstrate that CheXnet, when trained and tested on the DRR-RATE dataset, achieves sufficient to high AUC scores for the six common pathologies cited in common literature: Atelectasis, Cardiomegaly, Consolidation, Lung Lesion, Lung Opacity, and Pleural Effusion. Additionally, CheXnet trained on the CheXpert dataset can accurately identify several pathologies, even when operating out of distribution. This confirms that the generated DRR images effectively capture the essential pathology features from CT images. The dataset and labels are publicly accessible at https://huggingface.co/datasets/farrell236/DRR-RATE.

In this study, we propose an enhanced image restoration model, SUPIR, based on the integration of two low-rank adaptive (LoRA) modules with the Stable Diffusion XL (SDXL) framework. Our method leverages the advantages of LoRA to fine-tune SDXL models, thereby significantly improving image restoration quality and efficiency. We collect 2600 high-quality real-world images, each with detailed descriptive text, for training the model. The proposed method is evaluated on standard benchmarks and achieves excellent performance, demonstrated by higher peak signal-to-noise ratio (PSNR), lower learned perceptual image patch similarity (LPIPS), and higher structural similarity index measurement (SSIM) scores. These results underscore the effectiveness of combining LoRA with SDXL for advanced image restoration tasks, highlighting the potential of our approach in generating high-fidelity restored images.

X-ray imaging is a rapid and cost-effective tool for visualizing internal human anatomy. While multi-view X-ray imaging provides complementary information that enhances diagnosis, intervention, and education, acquiring images from multiple angles increases radiation exposure and complicates clinical workflows. To address these challenges, we propose a novel view-conditioned diffusion model for synthesizing multi-view X-ray images from a single view. Unlike prior methods, which are limited in angular range, resolution, and image quality, our approach leverages the Diffusion Transformer to preserve fine details and employs a weak-to-strong training strategy for stable high-resolution image generation. Experimental results demonstrate that our method generates higher-resolution outputs with improved control over viewing angles. This capability has significant implications not only for clinical applications but also for medical education and data extension, enabling the creation of diverse, high-quality datasets for training and analysis. Our code is available at https://github.com/xiechun298/SV-DRR.

Despite the proven significance of hyperspectral images (HSIs) in performing various computer vision tasks, its potential is adversely affected by the low-resolution (LR) property in the spatial domain, resulting from multiple physical factors. Inspired by recent advancements in deep generative models, we propose an HSI Super-resolution (SR) approach with Conditional Diffusion Models (HSR-Diff) that merges a high-resolution (HR) multispectral image (MSI) with the corresponding LR-HSI. HSR-Diff generates an HR-HSI via repeated refinement, in which the HR-HSI is initialized with pure Gaussian noise and iteratively refined. At each iteration, the noise is removed with a Conditional Denoising Transformer (CDF ormer) that is trained on denoising at different noise levels, conditioned on the hierarchical feature maps of HR-MSI and LR-HSI. In addition, a progressive learning strategy is employed to exploit the global information of full-resolution images. Systematic experiments have been conducted on four public datasets, demonstrating that HSR-Diff outperforms state-of-the-art methods.

Radiology report generation (RRG) has attracted significant attention due to its potential to reduce the workload of radiologists. Current RRG approaches are still unsatisfactory against clinical standards. This paper introduces a novel RRG method, LM-RRG, that integrates large models (LMs) with clinical quality reinforcement learning to generate accurate and comprehensive chest X-ray radiology reports. Our method first designs a large language model driven feature extractor to analyze and interpret different regions of the chest X-ray image, emphasizing specific regions with medical significance. Next, based on the large model's decoder, we develop a multimodal report generator that leverages multimodal prompts from visual features and textual instruction to produce the radiology report in an auto-regressive way. Finally, to better reflect the clinical significant and insignificant errors that radiologists would normally assign in the report, we introduce a novel clinical quality reinforcement learning strategy. It utilizes the radiology report clinical quality (RadCliQ) metric as a reward function in the learning process. Extensive experiments on the MIMIC-CXR and IU-Xray datasets demonstrate the superiority of our method over the state of the art.

Super-resolution (SR) techniques have recently been proposed to upscale the outputs of neural radiance fields (NeRF) and generate high-quality images with enhanced inference speeds. However, existing NeRF+SR methods increase training overhead by using extra input features, loss functions, and/or expensive training procedures such as knowledge distillation. In this paper, we aim to leverage SR for efficiency gains without costly training or architectural changes. Specifically, we build a simple NeRF+SR pipeline that directly combines existing modules, and we propose a lightweight augmentation technique, random patch sampling, for training. Compared to existing NeRF+SR methods, our pipeline mitigates the SR computing overhead and can be trained up to 23x faster, making it feasible to run on consumer devices such as the Apple MacBook. Experiments show our pipeline can upscale NeRF outputs by 2-4x while maintaining high quality, increasing inference speeds by up to 18x on an NVIDIA V100 GPU and 12.8x on an M1 Pro chip. We conclude that SR can be a simple but effective technique for improving the efficiency of NeRF models for consumer devices.

Developing an interpretable system for generating reports in chest X-ray (CXR) analysis is becoming increasingly crucial in Computer-aided Diagnosis (CAD) systems, enabling radiologists to comprehend the decisions made by these systems. Despite the growth of diverse datasets and methods focusing on report generation, there remains a notable gap in how closely these models' generated reports align with the interpretations of real radiologists. In this study, we tackle this challenge by initially introducing Fine-Grained CXR (FG-CXR) dataset, which provides fine-grained paired information between the captions generated by radiologists and the corresponding gaze attention heatmaps for each anatomy. Unlike existing datasets that include a raw sequence of gaze alongside a report, with significant misalignment between gaze location and report content, our FG-CXR dataset offers a more grained alignment between gaze attention and diagnosis transcript. Furthermore, our analysis reveals that simply applying black-box image captioning methods to generate reports cannot adequately explain which information in CXR is utilized and how long needs to attend to accurately generate reports. Consequently, we propose a novel explainable radiologist's attention generator network (Gen-XAI) that mimics the diagnosis process of radiologists, explicitly constraining its output to closely align with both radiologist's gaze attention and transcript. Finally, we perform extensive experiments to illustrate the effectiveness of our method. Our datasets and checkpoint is available at https://github.com/UARK-AICV/FG-CXR.

Recent advancements in super-resolution for License Plate Recognition (LPR) have sought to address challenges posed by low-resolution (LR) and degraded images in surveillance, traffic monitoring, and forensic applications. However, existing studies have relied on private datasets and simplistic degradation models. To address this gap, we introduce UFPR-SR-Plates, a novel dataset containing 10,000 tracks with 100,000 paired low and high-resolution license plate images captured under real-world conditions. We establish a benchmark using multiple sequential LR and high-resolution (HR) images per vehicle -- five of each -- and two state-of-the-art models for super-resolution of license plates. We also investigate three fusion strategies to evaluate how combining predictions from a leading Optical Character Recognition (OCR) model for multiple super-resolved license plates enhances overall performance. Our findings demonstrate that super-resolution significantly boosts LPR performance, with further improvements observed when applying majority vote-based fusion techniques. Specifically, the Layout-Aware and Character-Driven Network (LCDNet) model combined with the Majority Vote by Character Position (MVCP) strategy led to the highest recognition rates, increasing from 1.7% with low-resolution images to 31.1% with super-resolution, and up to 44.7% when combining OCR outputs from five super-resolved images. These findings underscore the critical role of super-resolution and temporal information in enhancing LPR accuracy under real-world, adverse conditions. The proposed dataset is publicly available to support further research and can be accessed at: https://valfride.github.io/nascimento2024toward/

Real-world image super-resolution (RWSR) is a long-standing problem as low-quality (LQ) images often have complex and unidentified degradations. Existing methods such as Generative Adversarial Networks (GANs) or continuous diffusion models present their own issues including GANs being difficult to train while continuous diffusion models requiring numerous inference steps. In this paper, we propose an Iterative Token Evaluation and Refinement (ITER) framework for RWSR, which utilizes a discrete diffusion model operating in the discrete token representation space, i.e., indexes of features extracted from a VQGAN codebook pre-trained with high-quality (HQ) images. We show that ITER is easier to train than GANs and more efficient than continuous diffusion models. Specifically, we divide RWSR into two sub-tasks, i.e., distortion removal and texture generation. Distortion removal involves simple HQ token prediction with LQ images, while texture generation uses a discrete diffusion model to iteratively refine the distortion removal output with a token refinement network. In particular, we propose to include a token evaluation network in the discrete diffusion process. It learns to evaluate which tokens are good restorations and helps to improve the iterative refinement results. Moreover, the evaluation network can first check status of the distortion removal output and then adaptively select total refinement steps needed, thereby maintaining a good balance between distortion removal and texture generation. Extensive experimental results show that ITER is easy to train and performs well within just 8 iterative steps. Our codes will be available publicly.

To satisfy the rapidly increasing demands on the large image (2K-8K) super-resolution (SR), prevailing methods follow two independent tracks: 1) accelerate existing networks by content-aware routing, and 2) design better super-resolution networks via token mixer refining. Despite directness, they encounter unavoidable defects (e.g., inflexible route or non-discriminative processing) limiting further improvements of quality-complexity trade-off. To erase the drawbacks, we integrate these schemes by proposing a content-aware mixer (CAMixer), which assigns convolution for simple contexts and additional deformable window-attention for sparse textures. Specifically, the CAMixer uses a learnable predictor to generate multiple bootstraps, including offsets for windows warping, a mask for classifying windows, and convolutional attentions for endowing convolution with the dynamic property, which modulates attention to include more useful textures self-adaptively and improves the representation capability of convolution. We further introduce a global classification loss to improve the accuracy of predictors. By simply stacking CAMixers, we obtain CAMixerSR which achieves superior performance on large-image SR, lightweight SR, and omnidirectional-image SR.

Guided depth map super-resolution (GDSR), as a hot topic in multi-modal image processing, aims to upsample low-resolution (LR) depth maps with additional information involved in high-resolution (HR) RGB images from the same scene. The critical step of this task is to effectively extract domain-shared and domain-private RGB/depth features. In addition, three detailed issues, namely blurry edges, noisy surfaces, and over-transferred RGB texture, need to be addressed. In this paper, we propose the Spherical Space feature Decomposition Network (SSDNet) to solve the above issues. To better model cross-modality features, Restormer block-based RGB/depth encoders are employed for extracting local-global features. Then, the extracted features are mapped to the spherical space to complete the separation of private features and the alignment of shared features. Shared features of RGB are fused with the depth features to complete the GDSR task. Subsequently, a spherical contrast refinement (SCR) module is proposed to further address the detail issues. Patches that are classified according to imperfect categories are input into the SCR module, where the patch features are pulled closer to the ground truth and pushed away from the corresponding imperfect samples in the spherical feature space via contrastive learning. Extensive experiments demonstrate that our method can achieve state-of-the-art results on four test datasets, as well as successfully generalize to real-world scenes. The code is available at https://github.com/Zhaozixiang1228/GDSR-SSDNet.

We propose 3D Super Resolution (3DSR), a novel 3D Gaussian-splatting-based super-resolution framework that leverages off-the-shelf diffusion-based 2D super-resolution models. 3DSR encourages 3D consistency across views via the use of an explicit 3D Gaussian-splatting-based scene representation. This makes the proposed 3DSR different from prior work, such as image upsampling or the use of video super-resolution, which either don't consider 3D consistency or aim to incorporate 3D consistency implicitly. Notably, our method enhances visual quality without additional fine-tuning, ensuring spatial coherence within the reconstructed scene. We evaluate 3DSR on MipNeRF360 and LLFF data, demonstrating that it produces high-resolution results that are visually compelling, while maintaining structural consistency in 3D reconstructions. Code will be released.

Radiology report generation (RRG) is a challenging task, as it requires a thorough understanding of medical images, integration of multiple temporal inputs, and accurate report generation. Effective interpretation of medical images, such as chest X-rays (CXRs), demands sophisticated visual-language reasoning to map visual findings to structured reports. Recent studies have shown that multimodal large language models (MLLMs) can acquire multimodal capabilities by aligning with pre-trained vision encoders. However, current approaches predominantly focus on single-image analysis or utilise rule-based symbolic processing to handle multiple images, thereby overlooking the essential temporal information derived from comparing current images with prior ones. To overcome this critical limitation, we introduce Libra, a temporal-aware MLLM tailored for CXR report generation using temporal images. Libra integrates a radiology-specific image encoder with a MLLM and utilises a novel Temporal Alignment Connector to capture and synthesise temporal information of images across different time points with unprecedented precision. Extensive experiments show that Libra achieves new state-of-the-art performance among the same parameter scale MLLMs for RRG tasks on the MIMIC-CXR. Specifically, Libra improves the RadCliQ metric by 12.9% and makes substantial gains across all lexical metrics compared to previous models.

Single-Image Super Resolution (SISR) is a classical computer vision problem and it has been studied for over decades. With the recent success of deep learning methods, recent work on SISR focuses solutions with deep learning methodologies and achieves state-of-the-art results. However most of the state-of-the-art SISR methods contain millions of parameters and layers, which limits their practical applications. In this paper, we propose a hardware (Synaptics Dolphin NPU) limitation aware, extremely lightweight quantization robust real-time super resolution network (XLSR). The proposed model's building block is inspired from root modules for Image classification. We successfully applied root modules to SISR problem, further more to make the model uint8 quantization robust we used Clipped ReLU at the last layer of the network and achieved great balance between reconstruction quality and runtime. Furthermore, although the proposed network contains 30x fewer parameters than VDSR its performance surpasses it on Div2K validation set. The network proved itself by winning Mobile AI 2021 Real-Time Single Image Super Resolution Challenge.

The development of successful artificial intelligence models for chest X-ray analysis relies on large, diverse datasets with high-quality annotations. While several databases of chest X-ray images have been released, most include disease diagnosis labels but lack detailed pixel-level anatomical segmentation labels. To address this gap, we introduce an extensive chest X-ray multi-center segmentation dataset with uniform and fine-grain anatomical annotations for images coming from six well-known publicly available databases: CANDID-PTX, ChestX-ray8, Chexpert, MIMIC-CXR-JPG, Padchest, and VinDr-CXR, resulting in 676,803 segmentation masks. Our methodology utilizes the HybridGNet model to ensure consistent and high-quality segmentations across all datasets. Rigorous validation, including expert physician evaluation and automatic quality control, was conducted to validate the resulting masks. Additionally, we provide individualized quality indices per mask and an overall quality estimation per dataset. This dataset serves as a valuable resource for the broader scientific community, streamlining the development and assessment of innovative methodologies in chest X-ray analysis. The CheXmask dataset is publicly available at: https://physionet.org/content/chexmask-cxr-segmentation-data/.

Although recent diffusion-based single-step super-resolution methods achieve better performance as compared to SinSR, they are computationally complex. To improve the performance of SinSR, we investigate preserving the high-frequency detail features during super-resolution (SR) because the downgraded images lack detailed information. For this purpose, we introduce a high-frequency perceptual loss by utilizing an invertible neural network (INN) pretrained on the ImageNet dataset. Different feature maps of pretrained INN produce different high-frequency aspects of an image. During the training phase, we impose to preserve the high-frequency features of super-resolved and ground truth (GT) images that improve the SR image quality during inference. Furthermore, we also utilize the Jenson-Shannon divergence between GT and SR images in the pretrained DINO-v2 embedding space to match their distribution. By introducing the high- frequency preserving loss and distribution matching constraint in the single-step diffusion-based SR (HF-Diff), we achieve a state-of-the-art CLIPIQA score in the benchmark RealSR, RealSet65, DIV2K-Val, and ImageNet datasets. Furthermore, the experimental results in several datasets demonstrate that our high-frequency perceptual loss yields better SR image quality than LPIPS and VGG-based perceptual losses. Our code will be released at https://github.com/shoaib-sami/HF-Diff.

Sparse-view 3D CT reconstruction aims to recover volumetric structures from a limited number of 2D X-ray projections. Existing feedforward methods are constrained by the scarcity of large-scale training datasets and the absence of direct and consistent 3D representations. In this paper, we propose an X-ray Large Reconstruction Model (X-LRM) for extremely sparse-view (<10 views) CT reconstruction. X-LRM consists of two key components: X-former and X-triplane. X-former can handle an arbitrary number of input views using an MLP-based image tokenizer and a Transformer-based encoder. The output tokens are then upsampled into our X-triplane representation, which models the 3D radiodensity as an implicit neural field. To support the training of X-LRM, we introduce Torso-16K, a large-scale dataset comprising over 16K volume-projection pairs of various torso organs. Extensive experiments demonstrate that X-LRM outperforms the state-of-the-art method by 1.5 dB and achieves 27times faster speed with better flexibility. Furthermore, the evaluation of lung segmentation tasks also suggests the practical value of our approach. Our code and dataset will be released at https://github.com/Richard-Guofeng-Zhang/X-LRM

Inspired by the success of large language models (LLMs), there is growing research interest in developing LLMs in the medical domain to assist clinicians. However, for hospitals, using closed-source commercial LLMs involves privacy issues, and developing open-source public LLMs requires large-scale computational resources, which are usually limited, especially in resource-efficient regions and low-income countries. We propose an open-source Small Language and Vision Assistant (SLaVA-CXR) that can be used for Chest X-Ray report automation. To efficiently train a small assistant, we first propose the Re^3Training method, which simulates the cognitive development of radiologists and optimizes the model in the Recognition, Reasoning, and Reporting training manner. Then, we introduce a data synthesis method, RADEX, which can generate a high-quality and diverse training corpus with privacy regulation compliance. The extensive experiments show that our SLaVA-CXR built on a 2.7B backbone not only outperforms but also achieves 6 times faster inference efficiency than previous state-of-the-art larger models.

It is widely agreed that reference-based super-resolution (RefSR) achieves superior results by referring to similar high quality images, compared to single image super-resolution (SISR). Intuitively, the more references, the better performance. However, previous RefSR methods have all focused on single-reference image training, while multiple reference images are often available in testing or practical applications. The root cause of such training-testing mismatch is the absence of publicly available multi-reference SR training datasets, which greatly hinders research efforts on multi-reference super-resolution. To this end, we construct a large-scale, multi-reference super-resolution dataset, named LMR. It contains 112,142 groups of 300x300 training images, which is 10x of the existing largest RefSR dataset. The image size is also much larger. More importantly, each group is equipped with 5 reference images with different similarity levels. Furthermore, we propose a new baseline method for multi-reference super-resolution: MRefSR, including a Multi-Reference Attention Module (MAM) for feature fusion of an arbitrary number of reference images, and a Spatial Aware Filtering Module (SAFM) for the fused feature selection. The proposed MRefSR achieves significant improvements over state-of-the-art approaches on both quantitative and qualitative evaluations. Our code and data would be made available soon.

Accurate Above-Ground Biomass (AGB) mapping at both large scale and high spatio-temporal resolution is essential for applications ranging from climate modeling to biodiversity assessment, and sustainable supply chain monitoring. At present, fine-grained AGB mapping relies on costly airborne laser scanning acquisition campaigns usually limited to regional scales. Initiatives such as the ESA CCI map attempt to generate global biomass products from diverse spaceborne sensors but at a coarser resolution. To enable global, high-resolution (HR) mapping, several works propose to regress AGB from HR satellite observations such as ESA Sentinel-1/2 images. We propose a novel way to address HR AGB estimation, by leveraging both HR satellite observations and existing low-resolution (LR) biomass products. We cast this problem as Guided Super-Resolution (GSR), aiming at upsampling LR biomass maps (sources) from 100 to 10 m resolution, using auxiliary HR co-registered satellite images (guides). We compare super-resolving AGB maps with and without guidance, against direct regression from satellite images, on the public BioMassters dataset. We observe that Multi-Scale Guidance (MSG) outperforms direct regression both for regression (-780 t/ha RMSE) and perception (+2.0 dB PSNR) metrics, and better captures high-biomass values, without significant computational overhead. Interestingly, unlike the RGB+Depth setting they were originally designed for, our best-performing AGB GSR approaches are those that most preserve the guide image texture. Our results make a strong case for adopting the GSR framework for accurate HR biomass mapping at scale. Our code and model weights are made publicly available (https://github.com/kaankaramanofficial/GSR4B).

The objective of image super-resolution is to generate clean and high-resolution images from degraded versions. Recent advancements in diffusion modeling have led to the emergence of various image super-resolution techniques that leverage pretrained text-to-image (T2I) models. Nevertheless, due to the prevalent severe degradation in low-resolution images and the inherent characteristics of diffusion models, achieving high-fidelity image restoration remains challenging. Existing methods often exhibit issues including semantic loss, artifacts, and the introduction of spurious content not present in the original image. To tackle this challenge, we propose Cascaded diffusion for Super-Resolution, CasSR , a novel method designed to produce highly detailed and realistic images. In particular, we develop a cascaded controllable diffusion model that aims to optimize the extraction of information from low-resolution images. This model generates a preliminary reference image to facilitate initial information extraction and degradation mitigation. Furthermore, we propose a multi-attention mechanism to enhance the T2I model's capability in maximizing the restoration of the original image content. Through a comprehensive blend of qualitative and quantitative analyses, we substantiate the efficacy and superiority of our approach.

Foundation models for medical imaging are typically pretrained on increasingly large datasets, following a "scale-at-all-costs" paradigm. However, this strategy faces two critical challenges: large-scale medical datasets often contain substantial redundancy and severe class imbalance that bias representation learning toward over-represented patterns, and indiscriminate training regardless of heterogeneity in data quality incurs considerable computational inefficiency. Here we demonstrate that active, principled data curation during pretraining can serve as a viable, cost-effective alternative to brute-force dataset enlargement. We introduce CheXficient, a chest X-ray (CXR) foundation model that selectively prioritizes informative training samples. CheXficient is pretrained on only 22.7% of 1,235,004 paired CXR images and reports while consuming under 27.3% of the total compute budget, yet achieving comparable or superior performance to its full-data counterpart and other large-scale pretrained models. We assess CheXficient across 20 individual benchmarks spanning 5 task types, including non-adapted off-the-shelf evaluations (zero-shot findings classification and crossmodal retrieval) and adapted downstream tasks (disease prediction, semantic segmentation, and radiology report generation). Further analyses show that CheXficient systematically prioritizes under-represented training samples, improving generalizability on long-tailed or rare conditions. Overall, our work offers practical insights into the data and computation demands for efficient pretraining and downstream adaptation of medical vision-language foundation models.

Super-resolution (SR) techniques have made major advances in reconstructing high-resolution images from low-resolution inputs. The increased resolution provides visual enhancement and utility for monitoring tasks. In particular, SR has been increasingly developed for satellite-based Earth observation, with applications in urban planning, agriculture, ecology, and disaster response. However, existing SR studies and benchmarks typically use fidelity metrics such as PSNR or SSIM, whereas the true utility of super-resolved images lies in supporting downstream tasks such as land cover classification, biomass estimation, and change detection. To bridge this gap, we introduce GeoSR-Bench, a downstream task-integrated SR benchmark dataset to evaluate SR models beyond fidelity metrics. GeoSR-Bench comprises spatially co-located, temporally aligned, and quality-controlled image pairs from about 36,000 locations across diverse land covers, spanning resolutions from 500m to 0.6m. To the best of our knowledge, GeoSR-Bench is the first SR benchmark that directly connects improved image resolution from SR models with downstream Earth monitoring tasks, including land cover segmentation, infrastructure mapping, and biophysical variable estimation. Using GeoSR-Bench, we benchmark GAN, transformer, neural operator, and diffusion-based SR models on perceptual quality and downstream task performance. We conduct experiments with 270 settings, covering 2 cross-platform SR tasks, 9 SR models, 3 downstream task models, and 5 downstream tasks for each SR task. The results show that improvements in traditional SR metrics often do not correlate with gains in task performance, and the correlations can be negative, indicating that these metrics provide limited guidance for selecting superior models for downstream tasks. This reveals the need to integrate downstream tasks into SR model development and evaluation.

Confocal fluorescence microscopy is one of the most accessible and widely used imaging techniques for the study of biological processes. Scanning confocal microscopy allows the capture of high-quality images from 3D samples, yet suffers from well-known limitations such as photobleaching and phototoxicity of specimens caused by intense light exposure, which limits its use in some applications, especially for living cells. Cellular damage can be alleviated by changing imaging parameters to reduce light exposure, often at the expense of image quality. Machine/deep learning methods for single-image super-resolution (SISR) can be applied to restore image quality by upscaling lower-resolution (LR) images to produce high-resolution images (HR). These SISR methods have been successfully applied to photo-realistic images due partly to the abundance of publicly available data. In contrast, the lack of publicly available data partly limits their application and success in scanning confocal microscopy. In this paper, we introduce a large scanning confocal microscopy dataset named SR-CACO-2 that is comprised of low- and high-resolution image pairs marked for three different fluorescent markers. It allows the evaluation of performance of SISR methods on three different upscaling levels (X2, X4, X8). SR-CACO-2 contains the human epithelial cell line Caco-2 (ATCC HTB-37), and it is composed of 22 tiles that have been translated in the form of 9,937 image patches for experiments with SISR methods. Given the new SR-CACO-2 dataset, we also provide benchmarking results for 15 state-of-the-art methods that are representative of the main SISR families. Results show that these methods have limited success in producing high-resolution textures, indicating that SR-CACO-2 represents a challenging problem. Our dataset, code and pretrained weights are available: https://github.com/sbelharbi/sr-caco-2.

Despite its fruitful applications in remote sensing, image super-resolution is troublesome to train and deploy as it handles different resolution magnifications with separate models. Accordingly, we propose a highly-applicable super-resolution framework called FunSR, which settles different magnifications with a unified model by exploiting context interaction within implicit function space. FunSR composes a functional representor, a functional interactor, and a functional parser. Specifically, the representor transforms the low-resolution image from Euclidean space to multi-scale pixel-wise function maps; the interactor enables pixel-wise function expression with global dependencies; and the parser, which is parameterized by the interactor's output, converts the discrete coordinates with additional attributes to RGB values. Extensive experimental results demonstrate that FunSR reports state-of-the-art performance on both fixed-magnification and continuous-magnification settings, meanwhile, it provides many friendly applications thanks to its unified nature.

Automated chest X-ray report generation has recently benefited from reinforcement learning (RL) and large language models. However, RL training often suffers from instability or limited exploration due to fixed Kullback-Leibler (KL) regularization and a static reference policy that accumulates KL pressure over time. We propose Response-Weighted and Validation-Anchored Policy Optimization (REVA-PO), a RL framework that stabilizes long-term training via Response-Weighted Regularization (RER) and Validation-Anchored Policy Reset (VAPR). RER dynamically adjusts per-response KL weights based on advantage and reference-policy entropy, relaxing constraints for high-quality responses while tightening them for low-quality ones. Complementarily, VAPR periodically synchronizes the reference and current policies to the best validation checkpoint, resetting accumulated regularization pressure to expand the viable exploration space. To ensure a robust starting point, we employ a three-stage pipeline consisting of warm-up training, classifier-guided supervised fine-tuning, and RL. Extensive evaluations on MIMIC-CXR and IU-Xray demonstrate that REVA-PO sets new state-of-the-art benchmarks in both linguistic quality and clinical accuracy. Notably, BLEU-4 improves by 5.1% on MIMIC-CXR and 3.6% on IU-Xray, while CheXpert F1 and RadGraph F1 scores increase by 4.5% and 12.8%, respectively, over prior leading methods. The code is publicly available at https://github.com/LiGuo12/REVA_PO/.

The automated generation of imaging reports proves invaluable in alleviating the workload of radiologists. A clinically applicable reports generation algorithm should demonstrate its effectiveness in producing reports that accurately describe radiology findings and attend to patient-specific indications. In this paper, we introduce a novel method, Structural Entities extraction and patient indications Incorporation (SEI) for chest X-ray report generation. Specifically, we employ a structural entities extraction (SEE) approach to eliminate presentation-style vocabulary in reports and improve the quality of factual entity sequences. This reduces the noise in the following cross-modal alignment module by aligning X-ray images with factual entity sequences in reports, thereby enhancing the precision of cross-modal alignment and further aiding the model in gradient-free retrieval of similar historical cases. Subsequently, we propose a cross-modal fusion network to integrate information from X-ray images, similar historical cases, and patient-specific indications. This process allows the text decoder to attend to discriminative features of X-ray images, assimilate historical diagnostic information from similar cases, and understand the examination intention of patients. This, in turn, assists in triggering the text decoder to produce high-quality reports. Experiments conducted on MIMIC-CXR validate the superiority of SEI over state-of-the-art approaches on both natural language generation and clinical efficacy metrics.

Super-Resolution (SR) is a fundamental computer vision task that aims to obtain a high-resolution clean image from the given low-resolution counterpart. This paper reviews the NTIRE 2021 Challenge on Video Super-Resolution. We present evaluation results from two competition tracks as well as the proposed solutions. Track 1 aims to develop conventional video SR methods focusing on the restoration quality. Track 2 assumes a more challenging environment with lower frame rates, casting spatio-temporal SR problem. In each competition, 247 and 223 participants have registered, respectively. During the final testing phase, 14 teams competed in each track to achieve state-of-the-art performance on video SR tasks.

This work studies Hyperspectral image (HSI) super-resolution (SR). HSI SR is characterized by high-dimensional data and a limited amount of training examples. This exacerbates the undesirable behaviors of neural networks such as memorization and sensitivity to out-of-distribution samples. This work addresses these issues with three contributions. First, we observe that HSI SR and RGB image SR are correlated and develop a novel multi-tasking network to train them jointly so that the auxiliary task RGB image SR can provide additional supervision. Second, we propose a simple, yet effective data augmentation routine, termed Spectral Mixup, to construct effective virtual training samples to enlarge the training set. Finally, we extend the network to a semi-supervised setting so that it can learn from datasets containing only low-resolution HSIs. With these contributions, our method is able to learn from heterogeneous datasets and lift the requirement for having a large amount of HD HSI training samples. Extensive experiments on four standard datasets show that our method outperforms existing methods significantly and underpin the relevance of our contributions. Code has been made available at https://github.com/kli8996/HSISR.

Reference-guided generation (e.g., object compositing, customization) has progressed rapidly, yet current pipelines share a fundamental limitation: the object-centric high-resolution reference image (HRRI) provided by users is downsampled to a fixed low-resolution (LR) before being fed into the model, so the fine-grained details are discarded before the output is even produced. In addition, the generation step then introduces its own artifacts (e.g., identity distortion) on top of this loss. Existing reference-guided generated content refinement (RefGCR) methods can correct some of these artifacts but still operate in the LR domain; reference-guided super-resolution (RefSR) methods recover resolution but assume natural-image degradations and ignore the artifact distribution of generative pipelines. To address both gaps in a single formulation, we introduce a new task: reference-guided generated content super-resolution-refinement (RefGC-SR^2), where the original HRRI is reused at the post-processing stage to recover lost details, refine generative artifacts, and upscale the output simultaneously. We construct the first real-world triplet data generation pipeline for this RefGC-SR^2 task, training a diptych-conditioned generator to synthesize paired low-quality anchors that public pretrained models cannot provide. We further present a frequency-aware diffusion transformer model for RefGC-SR^2 that selectively injects fine details from the HRRI while removing generative artifacts. Extensive experiments demonstrate that our RefGC-SR^2 model successfully (i) refines the object identity faithfully with respect to the reference, and (ii) recovers high-resolution details, so that the final result is significantly higher quality and practically more usable compared to existing RefGCR and RefSR baselines.

Image restoration methods like super-resolution and image synthesis have been successfully used in commercial cloud gaming products like NVIDIA's DLSS. However, restoration over gaming content is not well studied by the general public. The discrepancy is mainly caused by the lack of ground-truth gaming training data that match the test cases. Due to the unique characteristics of gaming content, the common approach of generating pseudo training data by degrading the original HR images results in inferior restoration performance. In this work, we develop GameIR, a large-scale high-quality computer-synthesized ground-truth dataset to fill in the blanks, targeting at two different applications. The first is super-resolution with deferred rendering, to support the gaming solution of rendering and transferring LR images only and restoring HR images on the client side. We provide 19200 LR-HR paired ground-truth frames coming from 640 videos rendered at 720p and 1440p for this task. The second is novel view synthesis (NVS), to support the multiview gaming solution of rendering and transferring part of the multiview frames and generating the remaining frames on the client side. This task has 57,600 HR frames from 960 videos of 160 scenes with 6 camera views. In addition to the RGB frames, the GBuffers during the deferred rendering stage are also provided, which can be used to help restoration. Furthermore, we evaluate several SOTA super-resolution algorithms and NeRF-based NVS algorithms over our dataset, which demonstrates the effectiveness of our ground-truth GameIR data in improving restoration performance for gaming content. Also, we test the method of incorporating the GBuffers as additional input information for helping super-resolution and NVS. We release our dataset and models to the general public to facilitate research on restoration methods over gaming content.

Ultra-high-resolution (UHR) remote sensing imagery couples kilometer-scale context with query-critical evidence that may occupy only a few pixels. Such vast spatial scale leads to a quadratic explosion of visual tokens and hinders the extraction of information from small objects. Previous works utilize direct downsampling, dense tiling, or global top-k pruning, which either compromise query-critical image details or incur unpredictable compute. In this paper, we propose UHR-BAT, a query-guided and region-faithful token compression framework to efficiently select visual tokens under a strict context budget. Specifically, we leverage text-guided, multi-scale importance estimation for visual tokens, effectively tackling the challenge of achieving precise yet low-cost feature extraction. Furthermore, by introducing region-wise preserve and merge strategies, we mitigate visual token redundancy, further driving down the computational budget. Experimental results show that UHR-BAT achieves state-of-the-art performance across various benchmarks. Code will be available at https://github.com/Yunkaidang/UHR.

Medical imaging is frequently used in clinical practice and trials for diagnosis and treatment. Writing imaging reports is time-consuming and can be error-prone for inexperienced radiologists. Therefore, automatically generating radiology reports is highly desired to lighten the workload of radiologists and accordingly promote clinical automation, which is an essential task to apply artificial intelligence to the medical domain. In this paper, we propose to generate radiology reports with memory-driven Transformer, where a relational memory is designed to record key information of the generation process and a memory-driven conditional layer normalization is applied to incorporating the memory into the decoder of Transformer. Experimental results on two prevailing radiology report datasets, IU X-Ray and MIMIC-CXR, show that our proposed approach outperforms previous models with respect to both language generation metrics and clinical evaluations. Particularly, this is the first work reporting the generation results on MIMIC-CXR to the best of our knowledge. Further analyses also demonstrate that our approach is able to generate long reports with necessary medical terms as well as meaningful image-text attention mappings.

3D super-resolution (3DSR) aims to reconstruct high-resolution (HR) 3D scenes from low-resolution (LR) multi-view images. Existing methods rely on dense LR inputs and per-scene optimization, which restricts the high-frequency priors for constructing HR 3D Gaussian Splatting (3DGS) to those inherited from pretrained 2D super-resolution (2DSR) models. This severely limits reconstruction fidelity, cross-scene generalization, and real-time usability. We propose to reformulate 3DSR as a direct feed-forward mapping from sparse LR views to HR 3DGS representations, enabling the model to autonomously learn 3D-specific high-frequency geometry and appearance from large-scale, multi-scene data. This fundamentally changes how 3DSR acquires high-frequency knowledge and enables robust generalization to unseen scenes. Specifically, we introduce SR3R, a feed-forward framework that directly predicts HR 3DGS representations from sparse LR views via the learned mapping network. To further enhance reconstruction fidelity, we introduce Gaussian offset learning and feature refinement, which stabilize reconstruction and sharpen high-frequency details. SR3R is plug-and-play and can be paired with any feed-forward 3DGS reconstruction backbone: the backbone provides an LR 3DGS scaffold, and SR3R upscales it to an HR 3DGS. Extensive experiments across three 3D benchmarks demonstrate that SR3R surpasses state-of-the-art (SOTA) 3DSR methods and achieves strong zero-shot generalization, even outperforming SOTA per-scene optimization methods on unseen scenes.

Recent advances in implicit neural representations (INRs) have shown significant promise in modeling visual signals for various low-vision tasks including image super-resolution (ISR). INR-based ISR methods typically learn continuous representations, providing flexibility for generating high-resolution images at any desired scale from their low-resolution counterparts. However, existing INR-based ISR methods utilize multi-layer perceptrons for parameterization in the network; this does not take account of the hierarchical structure existing in local sampling points and hence constrains the representation capability. In this paper, we propose a new Hierarchical encoding based Implicit Image Function for continuous image super-resolution, HIIF, which leverages a novel hierarchical positional encoding that enhances the local implicit representation, enabling it to capture fine details at multiple scales. Our approach also embeds a multi-head linear attention mechanism within the implicit attention network by taking additional non-local information into account. Our experiments show that, when integrated with different backbone encoders, HIIF outperforms the state-of-the-art continuous image super-resolution methods by up to 0.17dB in PSNR. The source code of HIIF will be made publicly available at www.github.com.

Vision-Language Models (VLMs) face significant challenges when dealing with the diverse resolutions and aspect ratios of real-world images, as most existing models rely on fixed, low-resolution inputs. While recent studies have explored integrating native resolution visual encoding to improve model performance, such efforts remain fragmented and lack a systematic framework within the open-source community. Moreover, existing benchmarks fall short in evaluating VLMs under varied visual conditions, often neglecting resolution as a critical factor. To address the "Resolution Dilemma" stemming from both model design and benchmark limitations, we introduce RC-Bench, a novel benchmark specifically designed to systematically evaluate VLM capabilities under extreme visual conditions, with an emphasis on resolution and aspect ratio variations. In conjunction, we propose NativeRes-LLaVA, an open-source training framework that empowers VLMs to effectively process images at their native resolutions and aspect ratios. Based on RC-Bench and NativeRes-LLaVA, we conduct comprehensive experiments on existing visual encoding strategies. The results show that Native Resolution Visual Encoding significantly improves the performance of VLMs on RC-Bench as well as other resolution-centric benchmarks. Code is available at https://github.com/Niujunbo2002/NativeRes-LLaVA.

A large-scale image-text pair dataset has greatly contributed to the development of vision-language pre-training (VLP) models, which enable zero-shot or few-shot classification without costly annotation. However, in the medical domain, the scarcity of data remains a significant challenge for developing a powerful VLP model. In this paper, we tackle the lack of image-text data in chest X-ray by expanding image-label pair as image-text pair via general prompt and utilizing multiple images and multiple sections in a radiologic report. We also design two contrastive losses, named ICL and TCL, for learning study-level characteristics of medical images and reports, respectively. Our model outperforms the state-of-the-art models trained under the same conditions. Also, enlarged dataset improve the discriminative power of our pre-trained model for classification, while sacrificing marginal retrieval performance. Code is available at https://github.com/kakaobrain/cxr-clip.

The hybrid deep models of Vision Transformer (ViT) and Convolution Neural Network (CNN) have emerged as a powerful class of backbones for vision tasks. Scaling up the input resolution of such hybrid backbones naturally strengthes model capacity, but inevitably suffers from heavy computational cost that scales quadratically. Instead, we present a new hybrid backbone with HIgh-Resolution Inputs (namely HIRI-ViT), that upgrades prevalent four-stage ViT to five-stage ViT tailored for high-resolution inputs. HIRI-ViT is built upon the seminal idea of decomposing the typical CNN operations into two parallel CNN branches in a cost-efficient manner. One high-resolution branch directly takes primary high-resolution features as inputs, but uses less convolution operations. The other low-resolution branch first performs down-sampling and then utilizes more convolution operations over such low-resolution features. Experiments on both recognition task (ImageNet-1K dataset) and dense prediction tasks (COCO and ADE20K datasets) demonstrate the superiority of HIRI-ViT. More remarkably, under comparable computational cost (sim5.0 GFLOPs), HIRI-ViT achieves to-date the best published Top-1 accuracy of 84.3% on ImageNet with 448times448 inputs, which absolutely improves 83.4% of iFormer-S by 0.9% with 224times224 inputs.

This paper reviews the NTIRE 2026 challenge on efficient single-image super-resolution with a focus on the proposed solutions and results. The aim of this challenge is to devise a network that reduces one or several aspects, such as runtime, parameters, and FLOPs, while maintaining PSNR of around 26.90 dB on the DIV2K_LSDIR_valid dataset, and 26.99 dB on the DIV2K_LSDIR_test dataset. The challenge had 95 registered participants, and 15 teams made valid submissions. They gauge the state-of-the-art results for efficient single-image super-resolution.

Radiologists play a crucial role by translating medical images into medical reports. However, the field faces staffing shortages and increasing workloads. While automated approaches using vision-language models (VLMs) show promise as assistants, they require exceptionally high accuracy. Most current VLMs in radiology rely solely on supervised fine-tuning (SFT). Meanwhile, in the general domain, additional preference fine-tuning has become standard practice. The challenge in radiology lies in the prohibitive cost of obtaining radiologist feedback. We propose a scalable automated preference alignment technique for VLMs in radiology, focusing on chest X-ray (CXR) report generation. Our method leverages publicly available datasets with an LLM-as-a-Judge mechanism, eliminating the need for additional expert radiologist feedback. We evaluate and benchmark five direct alignment algorithms (DAAs). Our results show up to a 57.4% improvement in average GREEN scores, a LLM-based metric for evaluating CXR reports, and a 9.2% increase in an average across six metrics (domain specific and general), compared to the SFT baseline. We study reward overoptimization via length exploitation, with reports lengthening by up to 3.2x. To assess a potential alignment tax, we benchmark on six additional diverse tasks, finding no significant degradations. A reader study involving four board-certified radiologists indicates win rates of up to 0.62 over the SFT baseline, while significantly penalizing verbosity. Our analysis provides actionable insights for the development of VLMs in high-stakes fields like radiology.

The applicability of current lesion segmentation models for chest X-rays (CXRs) has been limited both by a small number of target labels and the reliance on long, detailed expert-level text inputs, creating a barrier to practical use. To address these limitations, we introduce a new paradigm: instruction-guided lesion segmentation (ILS), which is designed to segment diverse lesion types based on simple, user-friendly instructions. Under this paradigm, we construct MIMIC-ILS, the first large-scale instruction-answer dataset for CXR lesion segmentation, using our fully automated multimodal pipeline that generates annotations from chest X-ray images and their corresponding reports. MIMIC-ILS contains 1.1M instruction-answer pairs derived from 192K images and 91K unique segmentation masks, covering seven major lesion types. To empirically demonstrate its utility, we introduce ROSALIA, a vision-language model fine-tuned on MIMIC-ILS. ROSALIA can segment diverse lesions and provide textual explanations in response to user instructions. The model achieves high segmentation and textual accuracy in our newly proposed task, highlighting the effectiveness of our pipeline and the value of MIMIC-ILS as a foundational resource for pixel-level CXR lesion grounding.

Pulmonary opacification is the inflammation in the lungs caused by many respiratory ailments, including the novel corona virus disease 2019 (COVID-19). Chest X-rays (CXRs) with such opacifications render regions of lungs imperceptible, making it difficult to perform automated image analysis on them. In this work, we focus on segmenting lungs from such abnormal CXRs as part of a pipeline aimed at automated risk scoring of COVID-19 from CXRs. We treat the high opacity regions as missing data and present a modified CNN-based image segmentation network that utilizes a deep generative model for data imputation. We train this model on normal CXRs with extensive data augmentation and demonstrate the usefulness of this model to extend to cases with extreme abnormalities.

Chest X-ray report generation (CXR-RG) has the potential to substantially alleviate radiologists' workload. However, conventional autoregressive vision--language models (VLMs) suffer from high inference latency due to sequential token decoding. Diffusion-based models offer a promising alternative through parallel generation, but they still require multiple denoising iterations. Compressing multi-step denoising to a single step could further reduce latency, but often degrades textual coherence due to the mean-field bias introduced by token-factorized denoisers. To address this challenge, we propose ECHO, an efficient diffusion-based VLM (dVLM) for chest X-ray report generation. ECHO enables stable one-step-per-block inference via a novel Direct Conditional Distillation (DCD) framework, which mitigates the mean-field limitation by constructing unfactorized supervision from on-policy diffusion trajectories to encode joint token dependencies. In addition, we introduce a Response-Asymmetric Diffusion (RAD) training strategy that further improves training efficiency while maintaining model effectiveness. Extensive experiments demonstrate that ECHO surpasses state-of-the-art autoregressive methods, improving RaTE and SemScore by 64.33\% and 60.58\% respectively, while achieving an 8times inference speedup without compromising clinical accuracy.

The Large Vision-Language Model (LVLM) field has seen significant advancements, yet its progression has been hindered by challenges in comprehending fine-grained visual content due to limited resolution. Recent efforts have aimed to enhance the high-resolution understanding capabilities of LVLMs, yet they remain capped at approximately 1500 x 1500 pixels and constrained to a relatively narrow resolution range. This paper represents InternLM-XComposer2-4KHD, a groundbreaking exploration into elevating LVLM resolution capabilities up to 4K HD (3840 x 1600) and beyond. Concurrently, considering the ultra-high resolution may not be necessary in all scenarios, it supports a wide range of diverse resolutions from 336 pixels to 4K standard, significantly broadening its scope of applicability. Specifically, this research advances the patch division paradigm by introducing a novel extension: dynamic resolution with automatic patch configuration. It maintains the training image aspect ratios while automatically varying patch counts and configuring layouts based on a pre-trained Vision Transformer (ViT) (336 x 336), leading to dynamic training resolution from 336 pixels to 4K standard. Our research demonstrates that scaling training resolution up to 4K HD leads to consistent performance enhancements without hitting the ceiling of potential improvements. InternLM-XComposer2-4KHD shows superb capability that matches or even surpasses GPT-4V and Gemini Pro in 10 of the 16 benchmarks. The InternLM-XComposer2-4KHD model series with 7B parameters are publicly available at https://github.com/InternLM/InternLM-XComposer.

Image Super-Resolution (SR) aims to recover a high-resolution image from its low-resolution counterpart, which has been affected by a specific degradation process. This is achieved by enhancing detail and visual quality. Recent advancements in transformer-based methods have remolded image super-resolution by enabling high-quality reconstructions surpassing previous deep-learning approaches like CNN and GAN-based. This effectively addresses the limitations of previous methods, such as limited receptive fields, poor global context capture, and challenges in high-frequency detail recovery. Additionally, the paper reviews recent trends and advancements in transformer-based SR models, exploring various innovative techniques and architectures that combine transformers with traditional networks to balance global and local contexts. These neoteric methods are critically analyzed, revealing promising yet unexplored gaps and potential directions for future research. Several visualizations of models and techniques are included to foster a holistic understanding of recent trends. This work seeks to offer a structured roadmap for researchers at the forefront of deep learning, specifically exploring the impact of transformers on super-resolution techniques.

High-resolution (HR) medical videos are vital for accurate diagnosis, yet are hard to acquire due to hardware limitations and physiological constraints. Clinically, the collected low-resolution (LR) medical videos present unique challenges for video super-resolution (VSR) models, including camera shake, noise, and abrupt frame transitions, which result in significant optical flow errors and alignment difficulties. Additionally, tissues and organs exhibit continuous and nuanced structures, but current VSR models are prone to introducing artifacts and distorted features that can mislead doctors. To this end, we propose MedVSR, a tailored framework for medical VSR. It first employs Cross State-Space Propagation (CSSP) to address the imprecise alignment by projecting distant frames as control matrices within state-space models, enabling the selective propagation of consistent and informative features to neighboring frames for effective alignment. Moreover, we design an Inner State-Space Reconstruction (ISSR) module that enhances tissue structures and reduces artifacts with joint long-range spatial feature learning and large-kernel short-range information aggregation. Experiments across four datasets in diverse medical scenarios, including endoscopy and cataract surgeries, show that MedVSR significantly outperforms existing VSR models in reconstruction performance and efficiency. Code released at https://github.com/CUHK-AIM-Group/MedVSR.

Most super-resolution (SR) models struggle with real-world low-resolution (LR) images. This issue arises because the degradation characteristics in the synthetic datasets differ from those in real-world LR images. Since SR models are trained on pairs of high-resolution (HR) and LR images generated by downsampling, they are optimized for simple degradation. However, real-world LR images contain complex degradation caused by factors such as the imaging process and JPEG compression. Due to these differences in degradation characteristics, most SR models perform poorly on real-world LR images. This study proposes a dataset generation method using undertrained image reconstruction models. These models have the property of reconstructing low-quality images with diverse degradation from input images. By leveraging this property, this study generates LR images with diverse degradation from HR images to construct the datasets. Fine-tuning pre-trained SR models on our generated datasets improves noise removal and blur reduction, enhancing performance on real-world LR images. Furthermore, an analysis of the datasets reveals that degradation diversity contributes to performance improvements, whereas color differences between HR and LR images may degrade performance. 11 pages, (11 figures and 2 tables)

Reconstructing high-resolution (HR) images from low-resolution (LR) inputs poses a significant challenge in image super-resolution (SR). While recent approaches have demonstrated the efficacy of intricate operations customized for various objectives, the straightforward stacking of these disparate operations can result in a substantial computational burden, hampering their practical utility. In response, we introduce SeemoRe, an efficient SR model employing expert mining. Our approach strategically incorporates experts at different levels, adopting a collaborative methodology. At the macro scale, our experts address rank-wise and spatial-wise informative features, providing a holistic understanding. Subsequently, the model delves into the subtleties of rank choice by leveraging a mixture of low-rank experts. By tapping into experts specialized in distinct key factors crucial for accurate SR, our model excels in uncovering intricate intra-feature details. This collaborative approach is reminiscent of the concept of "see more", allowing our model to achieve an optimal performance with minimal computational costs in efficient settings. The source will be publicly made available at https://github.com/eduardzamfir/seemoredetails

Most recent real-world image super-resolution (Real-ISR) methods employ pre-trained text-to-image (T2I) diffusion models to synthesize the high-quality image either from random Gaussian noise, which yields realistic results but is slow due to iterative denoising, or directly from the input low-quality image, which is efficient but at the price of lower output quality. These approaches train ControlNet or LoRA modules while keeping the pre-trained model fixed, which often introduces over-enhanced artifacts and hallucinations, suffering from the robustness to inputs of varying degradations. Recent visual autoregressive (AR) models, such as pre-trained Infinity, can provide strong T2I generation capabilities while offering superior efficiency by using the bitwise next-scale prediction strategy. Building upon next-scale prediction, we introduce a robust Real-ISR framework, namely Next-Scale Autoregressive Modeling (NSARM). Specifically, we train NSARM in two stages: a transformation network is first trained to map the input low-quality image to preliminary scales, followed by an end-to-end full-model fine-tuning. Such a comprehensive fine-tuning enhances the robustness of NSARM in Real-ISR tasks without compromising its generative capability. Extensive quantitative and qualitative evaluations demonstrate that as a pure AR model, NSARM achieves superior visual results over existing Real-ISR methods while maintaining a fast inference speed. Most importantly, it demonstrates much higher robustness to the quality of input images, showing stronger generalization performance. Project page: https://github.com/Xiangtaokong/NSARM

Enhancing low-resolution, low-frame-rate videos to high-resolution, high-frame-rate quality is essential for a seamless user experience, motivating advancements in Continuous Spatial-Temporal Video Super Resolution (C-STVSR). While prior methods employ Implicit Neural Representation (INR) for continuous encoding, they often struggle to capture the complexity of video data, relying on simple coordinate concatenation and pre-trained optical flow network for motion representation. Interestingly, we find that adding position encoding, contrary to common observations, does not improve-and even degrade performance. This issue becomes particularly pronounced when combined with pre-trained optical flow networks, which can limit the model's flexibility. To address these issues, we propose BF-STVSR, a C-STVSR framework with two key modules tailored to better represent spatial and temporal characteristics of video: 1) B-spline Mapper for smooth temporal interpolation, and 2) Fourier Mapper for capturing dominant spatial frequencies. Our approach achieves state-of-the-art PSNR and SSIM performance, showing enhanced spatial details and natural temporal consistency.

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases. However, acquiring high-quality OCTA images is challenging due to motion sensitivity and the high costs associated with software modifications for conventional OCT devices. Moreover, current deep learning methods for OCT-to-OCTA translation often overlook the vascular differences across retinal layers and struggle to reconstruct the intricate, dense vascular details necessary for reliable diagnosis. To overcome these limitations, we propose XOCT, a novel deep learning framework that integrates Cross-Dimensional Supervision (CDS) with a Multi-Scale Feature Fusion (MSFF) network for layer-aware vascular reconstruction. Our CDS module leverages 2D layer-wise en-face projections, generated via segmentation-weighted z-axis averaging, as supervisory signals to compel the network to learn distinct representations for each retinal layer through fine-grained, targeted guidance. Meanwhile, the MSFF module enhances vessel delineation through multi-scale feature extraction combined with a channel reweighting strategy, effectively capturing vascular details at multiple spatial scales. Our experiments on the OCTA-500 dataset demonstrate XOCT's improvements, especially for the en-face projections which are significant for clinical evaluation of retinal pathologies, underscoring its potential to enhance OCTA accessibility, reliability, and diagnostic value for ophthalmic disease detection and monitoring. The code is available at https://github.com/uci-cbcl/XOCT.

Contemporary image rescaling aims at embedding a high-resolution (HR) image into a low-resolution (LR) thumbnail image that contains embedded information for HR image reconstruction. Unlike traditional image super-resolution, this enables high-fidelity HR image restoration faithful to the original one, given the embedded information in the LR thumbnail. However, state-of-the-art image rescaling methods do not optimize the LR image file size for efficient sharing and fall short of real-time performance for ultra-high-resolution (e.g., 6K) image reconstruction. To address these two challenges, we propose a novel framework (HyperThumbnail) for real-time 6K rate-distortion-aware image rescaling. Our framework first embeds an HR image into a JPEG LR thumbnail by an encoder with our proposed quantization prediction module, which minimizes the file size of the embedding LR JPEG thumbnail while maximizing HR reconstruction quality. Then, an efficient frequency-aware decoder reconstructs a high-fidelity HR image from the LR one in real time. Extensive experiments demonstrate that our framework outperforms previous image rescaling baselines in rate-distortion performance and can perform 6K image reconstruction in real time.

In recent years, single image super-resolution (SISR) methods using deep convolution neural network (CNN) have achieved impressive results. Thanks to the powerful representation capabilities of the deep networks, numerous previous ways can learn the complex non-linear mapping between low-resolution (LR) image patches and their high-resolution (HR) versions. However, excessive convolutions will limit the application of super-resolution technology in low computing power devices. Besides, super-resolution of any arbitrary scale factor is a critical issue in practical applications, which has not been well solved in the previous approaches. To address these issues, we propose a lightweight information multi-distillation network (IMDN) by constructing the cascaded information multi-distillation blocks (IMDB), which contains distillation and selective fusion parts. Specifically, the distillation module extracts hierarchical features step-by-step, and fusion module aggregates them according to the importance of candidate features, which is evaluated by the proposed contrast-aware channel attention mechanism. To process real images with any sizes, we develop an adaptive cropping strategy (ACS) to super-resolve block-wise image patches using the same well-trained model. Extensive experiments suggest that the proposed method performs favorably against the state-of-the-art SR algorithms in term of visual quality, memory footprint, and inference time. Code is available at https://github.com/Zheng222/IMDN.

Generating a 3D dental volume from a single panoramic radiograph (PXR) could provide a low-radiation alternative to Cone-Beam Computed Tomography (CBCT), but the problem is highly underdetermined: panoramic acquisition integrates 3D attenuation along curved X-ray paths into a 2D image, leaving depth-resolved anatomy unobserved. Existing implicit and generative approaches often produce oversmoothed geometry or anatomically inconsistent hallucinations, lacking geometry-driven supervision and relying on smooth representations unable to precisely localize sharp anatomical boundaries. We propose X-Splat, the first Gaussian Splatting framework for generating CBCT-like 3D dental volumes from a single PXR. X-Splat uses the known panoramic acquisition geometry as a generation scaffold: learnable anisotropic Gaussian primitives are initialized along the X-ray paths that formed the input image and adjusted in a single feed-forward pass, constrained by Beer-Lambert reprojection and multi-view radiographic training supervision. A lightweight residual refiner adds dataset-level anatomical priors without overriding the geometry already resolved by the Gaussians. We train on synthetic PXR-CBCT pairs, enabling direct volumetric supervision without paired real scans. We further introduce segmentation-based geometry-aware metrics, providing the first evaluation of PXR-based generation over maxillofacial anatomy. X-Splat outperforms NeRF- and GAN-based baselines, recovering individual teeth, cortical boundaries, and alveolar structure, including the mandibular canal which prior methods fail to reconstruct. Code will be available at https://github.com/tomek1911/X-Splat

In the field of chest X-ray (CXR) diagnosis, existing works often focus solely on determining where a radiologist looks, typically through tasks such as detection, segmentation, or classification. However, these approaches are often designed as black-box models, lacking interpretability. In this paper, we introduce Interpretable Artificial Intelligence (I-AI) a novel and unified controllable interpretable pipeline for decoding the intense focus of radiologists in CXR diagnosis. Our I-AI addresses three key questions: where a radiologist looks, how long they focus on specific areas, and what findings they diagnose. By capturing the intensity of the radiologist's gaze, we provide a unified solution that offers insights into the cognitive process underlying radiological interpretation. Unlike current methods that rely on black-box machine learning models, which can be prone to extracting erroneous information from the entire input image during the diagnosis process, we tackle this issue by effectively masking out irrelevant information. Our proposed I-AI leverages a vision-language model, allowing for precise control over the interpretation process while ensuring the exclusion of irrelevant features. To train our I-AI model, we utilize an eye gaze dataset to extract anatomical gaze information and generate ground truth heatmaps. Through extensive experimentation, we demonstrate the efficacy of our method. We showcase that the attention heatmaps, designed to mimic radiologists' focus, encode sufficient and relevant information, enabling accurate classification tasks using only a portion of CXR. The code, checkpoints, and data are at https://github.com/UARK-AICV/IAI

Real-image super-resolution (Real-ISR) seeks to recover HR images from LR inputs with mixed, unknown degradations. While diffusion models surpass GANs in perceptual quality, they under-reconstruct high-frequency (HF) details due to a low-frequency (LF) bias and a depth-wise "low-first, high-later" hierarchy. We introduce FRAMER, a plug-and-play training scheme that exploits diffusion priors without changing the backbone or inference. At each denoising step, the final-layer feature map teaches all intermediate layers. Teacher and student feature maps are decomposed into LF/HF bands via FFT masks to align supervision with the model's internal frequency hierarchy. For LF, an Intra Contrastive Loss (IntraCL) stabilizes globally shared structure. For HF, an Inter Contrastive Loss (InterCL) sharpens instance-specific details using random-layer and in-batch negatives. Two adaptive modulators, Frequency-based Adaptive Weight (FAW) and Frequency-based Alignment Modulation (FAM), reweight per-layer LF/HF signals and gate distillation by current similarity. Across U-Net and DiT backbones (e.g., Stable Diffusion 2, 3), FRAMER consistently improves PSNR/SSIM and perceptual metrics (LPIPS, NIQE, MANIQA, MUSIQ). Ablations validate the final-layer teacher and random-layer negatives.

Diffusion-based approaches have recently driven remarkable progress in real-world image super-resolution (SR). However, existing methods still struggle to simultaneously preserve fine details and ensure high-fidelity reconstruction, often resulting in suboptimal visual quality. In this paper, we propose FiDeSR, a high-fidelity and detail-preserving one-step diffusion super-resolution framework. During training, we introduce a detail-aware weighting strategy that adaptively emphasizes regions where the model exhibits higher prediction errors. During inference, low- and high-frequency adaptive enhancers further refine the reconstruction without requiring model retraining, enabling flexible enhancement control. To further improve the reconstruction accuracy, FiDeSR incorporates a residual-in-residual noise refinement, which corrects prediction errors in the diffusion noise and enhances fine detail recovery. FiDeSR achieves superior real-world SR performance compared to existing diffusion-based methods, producing outputs with both high perceptual quality and faithful content restoration. The source code will be released at: https://github.com/Ar0Kim/FiDeSR.

In this work, we present QuickSRNet, an efficient super-resolution architecture for real-time applications on mobile platforms. Super-resolution clarifies, sharpens, and upscales an image to higher resolution. Applications such as gaming and video playback along with the ever-improving display capabilities of TVs, smartphones, and VR headsets are driving the need for efficient upscaling solutions. While existing deep learning-based super-resolution approaches achieve impressive results in terms of visual quality, enabling real-time DL-based super-resolution on mobile devices with compute, thermal, and power constraints is challenging. To address these challenges, we propose QuickSRNet, a simple yet effective architecture that provides better accuracy-to-latency trade-offs than existing neural architectures for single-image super resolution. We present training tricks to speed up existing residual-based super-resolution architectures while maintaining robustness to quantization. Our proposed architecture produces 1080p outputs via 2x upscaling in 2.2 ms on a modern smartphone, making it ideal for high-fps real-time applications.

With the rapid development of mobile devices, modern widely-used mobile phones typically allow users to capture 4K resolution (i.e., ultra-high-definition) images. However, for image demoireing, a challenging task in low-level vision, existing works are generally carried out on low-resolution or synthetic images. Hence, the effectiveness of these methods on 4K resolution images is still unknown. In this paper, we explore moire pattern removal for ultra-high-definition images. To this end, we propose the first ultra-high-definition demoireing dataset (UHDM), which contains 5,000 real-world 4K resolution image pairs, and conduct a benchmark study on current state-of-the-art methods. Further, we present an efficient baseline model ESDNet for tackling 4K moire images, wherein we build a semantic-aligned scale-aware module to address the scale variation of moire patterns. Extensive experiments manifest the effectiveness of our approach, which outperforms state-of-the-art methods by a large margin while being much more lightweight. Code and dataset are available at https://xinyu-andy.github.io/uhdm-page.

Omnidirectional images (ODIs) are commonly used in real-world visual tasks, and high-resolution ODIs help improve the performance of related visual tasks. Most existing super-resolution methods for ODIs use end-to-end learning strategies, resulting in inferior realness of generated images and a lack of effective out-of-domain generalization capabilities in training methods. Image generation methods represented by diffusion model provide strong priors for visual tasks and have been proven to be effectively applied to image restoration tasks. Leveraging the image priors of the Stable Diffusion (SD) model, we achieve omnidirectional image super-resolution with both fidelity and realness, dubbed as OmniSSR. Firstly, we transform the equirectangular projection (ERP) images into tangent projection (TP) images, whose distribution approximates the planar image domain. Then, we use SD to iteratively sample initial high-resolution results. At each denoising iteration, we further correct and update the initial results using the proposed Octadecaplex Tangent Information Interaction (OTII) and Gradient Decomposition (GD) technique to ensure better consistency. Finally, the TP images are transformed back to obtain the final high-resolution results. Our method is zero-shot, requiring no training or fine-tuning. Experiments of our method on two benchmark datasets demonstrate the effectiveness of our proposed method.