OTRec — disease ↔ target prioritization
Rank druggable-genome genes for a given disease (forward), or rank diseases for a given gene (reverse). Start typing a disease or gene — results appear automatically. Model and annotations: Open Targets Platform Release 25.12.
Disease
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5 200
0 0.95
Select a disease to begin
Label definitions and comparison coverage will appear here once you rank a disease.
Predicted targets — ranked over 17,073 candidate genes with tractability evidence or a known drug
Examples
Research screening tool, not clinical evidence — most predicted candidates will not progress in development.
If you use OTRec, please cite: Ofer D., Linial M. OTRec: A Deep Learning Recommender for Druggable Disease–Target Prioritization. bioRxiv 2025.12.21.695803, doi:10.64898/2025.12.21.695803 · Code on GitHub